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Epigenetics and chromosome biology

Section edited by Cesar Martins

This section incorporates all aspects of chromosome biology and epigenetics including but not limited to: molecular cytogenetics, comparative cytogenetics, studies investigating epigenetics, imprinting, and methylation, cytogenetics and karotyping.

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  1. Content type: Research article

    The bisexual fertile tetraploid fish is important in biological evolution. Tetraploid fish fertility is the key factor for stable inheritance. Therefore, elucidating tetraploid fish fertility at the molecular ...

    Authors: Rong Zhou, Yanhong Wu, Min Tao, Chun Zhang and Shaojun Liu

    Citation: BMC Genetics 2015 16:119

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  2. Content type: Research article

    Several reports indicate a commonly deleted chromosomal region independent from, and distal to the TP53 locus in a variety of human tumors. In a previous study, we reported a similar finding in a rat tumor model ...

    Authors: Carola Hedberg Oldfors, Diego Garcia Dios, Anna Linder, Kittichate Visuttijai, Emma Samuelson, Sandra Karlsson, Staffan Nilsson and Afrouz Behboudi

    Citation: BMC Genetics 2015 16:80

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  3. Content type: Research article

    X-chromosome inactivation silences one X chromosome in females to achieve dosage compensation with the single X chromosome in males. While most genes are silenced on the inactive X chromosome, the gene for the...

    Authors: Andrew G Chapman, Allison M Cotton, Angela D Kelsey and Carolyn J Brown

    Citation: BMC Genetics 2014 15:89

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  4. Content type: Research article

    Preeclampsia reduces placental expression and activity of 11β-hydroxysteroid dehydrogenase type 2 (HSD11B2), leading to an increase in fetal glucocordicoids. The latter has been proposed to be associated with ...

    Authors: Wensheng Hu, Xiaoling Weng, Minyue Dong, Yun Liu, Wenjuan Li and Hefeng Huang

    Citation: BMC Genetics 2014 15:96

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  5. Content type: Research article

    Allopolyploids generally undergo bivalent pairing at meiosis because only homologous chromosomes pair up. On the other hand, several studies have documented abnormal chromosome behavior during mitosis and meio...

    Authors: Qinbo Qin, Yude Wang, Juan Wang, Jing Dai, Yun Liu and Shaojun Liu

    Citation: BMC Genetics 2014 15:95

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  6. Content type: Research article

    Mussels of the genus Mytilus present morphologically similar karyotypes that are presumably conserved. The absence of chromosome painting probes in bivalves makes difficult verifying this hypothesis. In this cont...

    Authors: Concepción Pérez-García, Paloma Morán and Juan J Pasantes

    Citation: BMC Genetics 2014 15:84

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  7. Content type: Research article

    Aberrant hypermethylation of gene promoter regions is a primary mechanism by which tumor suppressor genes become inactivated in breast cancer. Epigenetic inactivation of the protein tyrosine phosphatase recept...

    Authors: Shao-ying Li, Rong Li, Yu-li Chen, Li-kuang Xiong, Hui-lin Wang, Lei Rong and Rong-cheng Luo

    Citation: BMC Genetics 2014 15:67

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  8. Content type: Research article

    Hypsiboas species have been divided into seven groups using morphological and genetic characters, but for most of the species, there is no cytogenetic information available. A cytogenetic analysis using conventio...

    Authors: Thais Lemos de Mattos, Ana Carolina Coelho, Carlos Henrique Schneider, David Otávio Carmo Telles, Marcelo Menin and Maria Claudia Gross

    Citation: BMC Genetics 2014 15:43

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  9. Content type: Research article

    Evolution of sturgeons and paddlefishes (order Acipenseriformes) is inherently connected with polyploidization events which resulted in differentiation of ploidy levels and chromosome numbers of present acipen...

    Authors: Miloš Havelka, Martin Hulák, Petr Ráb, Marie Rábová, Dietmar Lieckfeldt, Arne Ludwig, Marek Rodina, David Gela, Martin Pšenička, Dmytro Bytyutskyy and Martin Flajšhans

    Citation: BMC Genetics 2014 15:5

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  10. Content type: Research article

    The genus Micronycteris is a diverse group of phyllostomid bats currently comprising 11 species, with diploid number (2n) ranging from 26 to 40 chromosomes. The karyotypic relationships within Micronycteris and b...

    Authors: Talita FA Ribas, Luis RR Rodrigues, Cleusa Y Nagamachi, Anderson JB Gomes, Thayse CM Benathar, Patricia CM O’Brien, Fengtang Yang, Malcolm A Ferguson-Smith and Julio C Pieczarka

    Citation: BMC Genetics 2013 14:119

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  11. Content type: Research article

    Hybridization is a useful strategy to alter the genotypes and phenotypes of the offspring. It could transfer the genome of one species to another through combing the different genome of parents in the hybrid o...

    Authors: Weiguo He, Lihua Xie, Tangluo Li, Shaojun Liu, Jun Xiao, Jie Hu, Jing Wang, Qinbo Qin and Yun Liu

    Citation: BMC Genetics 2013 14:110

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  12. Content type: Research article

    Natural polyploidy has played an important role during the speciation and evolution of vertebrates, including anurans, with more than 55 described cases. The species of the Phyllomedusa burmeisteri group are most...

    Authors: Simone Lilian Gruber, Ana Paula Zampieri Silva, Célio Fernando Baptista Haddad and Sanae Kasahara

    Citation: BMC Genetics 2013 14:75

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  13. Content type: Research article

    The taxonomic and phylogenetic relationships of the genus Phyllomedusa have been amply discussed. The marked morphological similarities among some species hamper the reliable identification of specimens and may o...

    Authors: Daniel Pacheco Bruschi, Carmen Sílvia Busin, Luís Felipe Toledo, Gilda Andrade Vasconcellos, Christine Strussmann, Luiz Norberto Weber, Albertina Pimentel Lima, Jucivaldo Dias Lima and Shirlei Maria Recco-Pimentel

    Citation: BMC Genetics 2013 14:70

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  14. Content type: Research article

    The Leporinus genus, belonging to the Anostomidae family, is an interesting model for studies of sex chromosome evolution in fish, particularly because of the presence of heteromorphic sex chromosomes only in som...

    Authors: Patrícia Pasquali Parise-Maltempi, Edson Lourenço da Silva, Willem Rens, Frances Dearden, Patricia CM O’Brien, Vladimir Trifonov and Malcolm A Ferguson-Smith

    Citation: BMC Genetics 2013 14:60

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  15. Content type: Methodology article

    As a well-known epigenomic modification, DNA methylation is found to be common in plants and plays an important role in many biological processes. Relying on the unique feature of methylation-dependent digesti...

    Authors: Xiaojun Huang, Hanlin Lu, Jun-Wen Wang, Liqin Xu, Siyang Liu, Jihua Sun and Fei Gao

    Citation: BMC Genetics 2013 14:56

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  16. Content type: Research article

    hiPSCs are generated through epigenetic reprogramming of somatic tissue. Genomic imprinting is an epigenetic phenomenon through which monoallelic gene expression is regulated in a parent-of-origin-specific man...

    Authors: Hitoshi Hiura, Masashi Toyoda, Hiroaki Okae, Masahiro Sakurai, Naoko Miyauchi, Akiko Sato, Nobutaka Kiyokawa, Hajime Okita, Yoshitaka Miyagawa, Hidenori Akutsu, Koichiro Nishino, Akihiro Umezawa and Takahiro Arima

    Citation: BMC Genetics 2013 14:32

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  17. Content type: Research article

    Hybridogenesis (hemiclonal inheritance) is a kind of clonal reproduction in which hybrids between parental species are reproduced by crossing with one of the parental species. European water frogs (Pelophylax esc...

    Authors: Dmitry Dedukh, Glib Mazepa, Dmitry Shabanov, Juriy Rosanov, Spartak Litvinchuk, Leo Borkin, Alsu Saifitdinova and Alla Krasikova

    Citation: BMC Genetics 2013 14:26

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  18. Content type: Research article

    Proechimys is the most diverse genus in family Echimyidae, comprising 25 species (two of which are polytypic) and 39 taxa. Despite the numerous forms of this rodent and their abundance in nature, there are many t...

    Authors: Paulo JS Amaral, Cleusa Y Nagamachi, Renata CR Noronha, Marlyson JR Costa, Adenilson L Pereira, Rogerio V Rossi, Ana C Mendes-Oliveira and Julio C Pieczarka

    Citation: BMC Genetics 2013 14:21

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