Section edited by Federico Canzian
This section incorporates all aspects of the functional analysis of genes and genomes including but not limited to: sequence analysis and genotyping approaches to finding functional variation in genes and gene families, experimental studies of gene function, transcriptional regulation and gene expression.
Research article
Allotetraploid F1 hybrids (4nF1) (AABB, 4n = 148) were generated from the distant hybridization of Carassius auratus red var. (RCC) (AA, 2n = 100) (♀) × Megalobrama amblycephala (BSB) (BB, 2n = 48) (♂). It has be...
BMC Genetics 2017 18:86
Published on: 11 October 2017
Research article
Understanding the molecular basis of insecticide resistance is key to improve the surveillance and monitoring of malaria vector populations under control. In the major malaria vector Anopheles funestus, little is...
BMC Genetics 2017 18:76
Published on: 9 August 2017
Research article
Misidentification of the chicken leptin gene has hampered research of leptin signaling in this species for almost two decades. Recently, the genuine leptin gene with a GC-rich (~70%) repetitive-sequence content w...
BMC Genetics 2017 18:77
Published on: 9 August 2017
Research article
Persons living with HIV/AIDS (PLWHA) are at an increased risk of suicide. Increased suicidal risk is a predictor of future attempted and completed suicides and has been associated with poor quality of life and...
BMC Genetics 2017 18:71
Published on: 25 July 2017
Research article
Neuregulin 3 (NRG3) plays a key role in central nervous system development and is a strong candidate for human mental disorders. Thus, genetic variation in NRG3 may have some impact on a variety of phenotypes in ...
BMC Genetics 2017 18:69
Published on: 21 July 2017
Research article
The determinants of malaria parasite virulence is not entirely known, but the outcome of malaria infection (asymptomatic or symptomatic) has been associated with carriage of distinct parasite genotypes. Allele...
BMC Genetics 2017 18:67
Published on: 17 July 2017
Research article
Sucrose non-fermenting-1-related protein kinase 2 (SnRK2) is a plant-specific serine/threonine kinase family involved in the abscisic acid (ABA) signaling pathway and responds to osmotic stress. A genome-wide ...
BMC Genetics 2017 18:54
Published on: 12 June 2017
Research article
Mesencephalic Astrocyte-derived Neurotrophic Factor (MANF) and Cerebral Dopamine Neurotrophic Factor (CDNF) form an evolutionarily conserved family of neurotrophic factors. Orthologues for MANF/CDNF are the on...
BMC Genetics 2017 18:52
Published on: 2 June 2017
Research article
Our previous RNA-sequencing study revealed that the ATF3 and CDKN1A genes were remarkably differentially expressed between the mammary glands of lactating Holstein cows with extremely high and low milk protein an...
BMC Genetics 2017 18:47
Published on: 19 May 2017
Research article
The SnRKs (sucrose non-fermenting 1 related protein kinase) are a gene family coding for Ser/Thr protein kinases and play important roles in linking the tolerance and metabolic responses of plants to abiotic s...
BMC Genetics 2017 18:41
Published on: 15 May 2017
Methodology
Genetic interactions are keys to understand complex traits and evolution. Epistasis analysis is an effective method to map genetic interactions. Large-scale quantitative epistasis analysis has been well establ...
BMC Genetics 2017 18:42
Published on: 15 May 2017
Research article
Naturally occurring mutations in growth and differentiation factor 9 (GDF9) or bone morphogenetic protein 15 (BMP15) genes are associated with increased ovulation rate (OR) and litter size (LS) but also sterility...
BMC Genetics 2017 18:43
Published on: 15 May 2017
Research article
Two key questions in understanding the genetic control of behaviors are: what genes are involved and how these genes interact. To answer these questions at a systems level, we conducted high-content profiling of
BMC Genetics 2017 18:40
Published on: 12 May 2017
Research article
Oculocutaneous Albinism (OCA) is an autosomal recessive inherited condition that affects the pigmentation of eyes, hair and skin. The OCA phenotype may be caused by mutations in the tyrosinase gene (TYR), whic...
BMC Genetics 2017 18:39
Published on: 5 May 2017
Research article
Plant height (PH) and ear height (EH) are two important agronomic traits in maize selection breeding. F1 hybrid exhibit significant heterosis for PH and EH as compared to their parental inbred lines. To understan...
BMC Genetics 2017 18:36
Published on: 17 April 2017
Research article
Auxin plays an important role in regulating plant growth and development as well as in the response of plants to abiotic stresses. Auxin is transported by three kinds of major protein families, including the A...
BMC Genetics 2017 18:33
Published on: 7 April 2017
Research article
Arabian horses are believed to be one of the oldest and most influential horse breeds in the world. Blood is the main tissue involved in maintaining body homeostasis, and it is considered a marker of the proce...
BMC Genetics 2017 18:31
Published on: 5 April 2017
Research article
Avian pathogenic E. coli (APEC) can lead to a loss in millions of dollars in poultry annually because of mortality and produce contamination. Studies have verified that many immune-related genes undergo changes i...
BMC Genetics 2017 18:21
Published on: 7 March 2017
Research article
Although Pomacea canaliculata is native to South and Central America, it has become one of the most abundant invasive species worldwide and causes extensive damage to agriculture and horticulture. Conventional ph...
BMC Genetics 2017 18:18
Published on: 22 February 2017
Research article
Trichoderma spp. can establish beneficial interactions with plants by promoting plant growth and defense systems, as well as, antagonizing fungal phytopathogens in mycoparasitic intera...
BMC Genetics 2017 18:16
Published on: 15 February 2017
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