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  1. Content type: Research article

    Understanding the relationship between genetic admixture and performances is crucial for the success of crossbreeding programs. Use of small sets of ancestry informative markers (AIMs) is a cost effective opti...

    Authors: Tesfaye Getachew, Heather J. Huson, Maria Wurzinger, Jörg Burgstaller, Solomon Gizaw, Aynalem Haile, Barbara Rischkowsky, Gottfried Brem, Solomon Antwi Boison, Gábor Mészáros, Ally Okeyo Mwai and Johann Sölkner

    Citation: BMC Genetics 2017 18:80

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  2. Content type: Research article

    Seedling establishment is a crucial and vulnerable stage in the crop life cycle which determines further plant growth. While many studies are available on salt tolerance at the vegetative stage, the mechanisms...

    Authors: Wentao Xue, Jun Yan, Gang Zhao, Yan Jiang, Jianping Cheng, Luigi Cattivelli and Alessandro Tondelli

    Citation: BMC Genetics 2017 18:79

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  3. Content type: Research article

    Undernutrition is an increasingly common problem. Insufficient calorie intake and nutrient deficiencies during pregnancy may have an impact not only on the mother, but may also alter metabolism in the infant. ...

    Authors: Joanna Nowacka-Woszuk, Zofia E. Madeja and Agata Chmurzynska

    Citation: BMC Genetics 2017 18:78

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  4. Content type: Research article

    Understanding the molecular basis of insecticide resistance is key to improve the surveillance and monitoring of malaria vector populations under control. In the major malaria vector Anopheles funestus, little is...

    Authors: Helen Irving and Charles S. Wondji

    Citation: BMC Genetics 2017 18:76

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  5. Content type: Research article

    Misidentification of the chicken leptin gene has hampered research of leptin signaling in this species for almost two decades. Recently, the genuine leptin gene with a GC-rich (~70%) repetitive-sequence content w...

    Authors: Eyal Seroussi, Frédérique Pitel, Sophie Leroux, Mireille Morisson, Susanne Bornelöv, Shoval Miyara, Sara Yosefi, Larry A. Cogburn, David W. Burt, Leif Anderson and Miriam Friedman-Einat

    Citation: BMC Genetics 2017 18:77

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    The Correction to this article has been published in BMC Genetics 2017 18:113

  6. Content type: Research article

    The allotetraploid hybrid fish (4nAT) that was created in a previous study through an intergeneric cross between red crucian carp (Carassius auratus red var., ♀) and common carp (Cyprinus carpio L., ♂) provided a...

    Authors: Lihai Ye, Chun Zhang, Xiaojun Tang, Yiyi Chen and Shaojun Liu

    Citation: BMC Genetics 2017 18:75

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  7. Content type: Research article

    Surveillance for bovine genetic diseases in Denmark identified a hitherto unreported congenital syndrome occurring among progeny of a Holstein sire used for artificial breeding. A genetic aetiology due to a do...

    Authors: Jørgen S. Agerholm, Fintan J. McEvoy, Steffen Heegaard, Carole Charlier, Vidhya Jagannathan and Cord Drögemüller

    Citation: BMC Genetics 2017 18:74

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  8. Content type: Research article

    Korarima [Aframomum corrorima (Braun) P.C.M. Jansen] is a spice crop native to Ethiopia. Understanding the extent and partitioning of diversity within and among crop landraces and their wild relatives is among th...

    Authors: Dagmawit Chombe, Endashaw Bekele, Tomas Bryngelsson, Abel Teshome and Mulatu Geleta

    Citation: BMC Genetics 2017 18:72

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  9. Content type: Research article

    Persons living with HIV/AIDS (PLWHA) are at an increased risk of suicide. Increased suicidal risk is a predictor of future attempted and completed suicides and has been associated with poor quality of life and...

    Authors: Allan Kalungi, Soraya Seedat, Sian M. J. Hemmings, Lize van der Merwe, Moses L. Joloba, Ann Nanteza, Noeline Nakassujja, Harriet Birabwa, Jennifer Serwanga, Pontiano Kaleebu and Eugene Kinyanda

    Citation: BMC Genetics 2017 18:71

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  10. Content type: Methodology Article

    Genome-wide association studies involve detecting association between millions of genetic variants and a trait, which typically use univariate regression to test association between each single variant and the...

    Authors: Jaron Arbet, Matt McGue, Snigdhansu Chatterjee and Saonli Basu

    Citation: BMC Genetics 2017 18:70

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  11. Content type: Research article

    Neuregulin 3 (NRG3) plays a key role in central nervous system development and is a strong candidate for human mental disorders. Thus, genetic variation in NRG3 may have some impact on a variety of phenotypes in ...

    Authors: Hideaki Abe, Daiki Aoya, Hiro-aki Takeuchi and Miho Inoue-Murayama

    Citation: BMC Genetics 2017 18:69

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  12. Content type: Research article

    Investments in genetic selection have played a major role in the New Zealand sheep industry competitiveness. Selection may erode genetic diversity, which is a crucial factor for the success of breeding program...

    Authors: Vincent Prieur, Shannon M. Clarke, Luiz F. Brito, John C. McEwan, Michael A. Lee, Rudiger Brauning, Ken G. Dodds and Benoît Auvray

    Citation: BMC Genetics 2017 18:68

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  13. Content type: Research article

    The determinants of malaria parasite virulence is not entirely known, but the outcome of malaria infection (asymptomatic or symptomatic) has been associated with carriage of distinct parasite genotypes. Allele...

    Authors: Akua Kyerewaa Botwe, Kwaku Poku Asante, George Adjei, Samuel Assafuah, David Dosoo and Seth Owusu-Agyei

    Citation: BMC Genetics 2017 18:67

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  14. Content type: Research article

    Although Tellinidae is one of the largest and most diverse families of bivalves, its taxonomy is utterly chaotic. This is mainly due to the morphological diversity and homoplasy displayed by their shells and t...

    Authors: Daniel García-Souto, Gonzalo Ríos and Juan J. Pasantes

    Citation: BMC Genetics 2017 18:66

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  15. Content type: Research article

    Cowpea [Vigna unguiculata (L.) Walp.] is one of the most important legumes in tropical and semi-arid regions. However, there is relatively little genomic information available for genetic research on and breeding...

    Authors: Honglin Chen, Lixia Wang, Xiaoyan Liu, Liangliang Hu, Suhua Wang and Xuzhen Cheng

    Citation: BMC Genetics 2017 18:65

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  16. Content type: Research article

    Piglet splay leg syndrome (PSL) is one of the most frequent genetic defects, and can cause considerable economic loss in pig production. The present understanding of etiology and pathogenesis of PSL is poor. T...

    Authors: Xingjie Hao, Graham Plastow, Chunyan Zhang, Sutong Xu, Zhiqiu Hu, Tianfu Yang, Kai Wang, Huawei Yang, Xiaoxue Yin, Shili Liu, Zhenghua Wang, Zhiquan Wang and Shujun Zhang

    Citation: BMC Genetics 2017 18:64

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  17. Content type: Research article

    Using a genome-wide association study strategy, our previous study discovered 19 significant single-nucleotide polymorphisms (SNPs) related to semen production traits in Chinese Holstein bulls. Among them, thr...

    Authors: Shuli Liu, Hongwei Yin, Cong Li, Chunhua Qin, Wentao Cai, Mingyue Cao and Shengli Zhang

    Citation: BMC Genetics 2017 18:63

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  18. Content type: Research article

    Copy number variations are genome polymorphism that influence phenotypic variation and are an important source of genetic variation in populations. The aim of this study was to investigate genetic variability ...

    Authors: E. Gorla, M. C. Cozzi, S. I. Román-Ponce, F. J. Ruiz López, V. E. Vega-Murillo, S. Cerolini, A. Bagnato and M. G. Strillacci

    Citation: BMC Genetics 2017 18:61

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  19. Content type: Research article

    Genome-wide investigation of molecular mechanisms for high-altitude adaptation has attracted great attention in the last few years. In order to understand the contribution of gene expression level variations t...

    Authors: Weizhao Yang, Yin Qi, Bin Lu, Liang Qiao, Yayong Wu and Jinzhong Fu

    Citation: BMC Genetics 2017 18:62

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  20. Content type: Research article

    Cattle are bred for, amongst other factors, specific traits, including parasite resistance and adaptation to climate. However, the influence and inheritance of mitochondrial DNA (mtDNA) are not usually conside...

    Authors: Kanokwan Srirattana, Kieren McCosker, Tim Schatz and Justin C. St. John

    Citation: BMC Genetics 2017 18:59

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  21. Content type: Research article

    Circadian rhythms regulate key biological processes and the dysregulation of the intrinsic clock mechanism affects sleep patterns and obesity onset. The CLOCK (circadian locomotor output cycles protein kaput) gen...

    Authors: Pia Riestra, Samson Y Gebreab, Ruihua Xu, Rumana J Khan, Amadou Gaye, Adolfo Correa, Nancy Min, Mario Sims and Sharon K Davis

    Citation: BMC Genetics 2017 18:58

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  22. Content type: Research article

    The levels of circulating cytokines fluctuate with age, acute illness, and chronic disease, and are predictive of mortality; this is also true for patterns of DNA (CpG) methylation. Given that immune cells are...

    Authors: Chris P. Verschoor, Lisa M. McEwen, Vikas Kohli, Christina Wolfson, Dawn ME. Bowdish, Parminder Raina, Michael S. Kobor and Cynthia Balion

    Citation: BMC Genetics 2017 18:57

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  23. Content type: Research article

    Correlated genetic response in survival to selection for high growth has not been reported in giant freshwater prawn (GFP) (Macrobrachium rosenbergii). The main aim of this study was to measure genetic changes an...

    Authors: Nguyen Thanh Vu, Trinh Quoc Trong and Nguyen Hong Nguyen

    Citation: BMC Genetics 2017 18:56

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  24. Content type: Research article

    Sucrose non-fermenting-1-related protein kinase 2 (SnRK2) is a plant-specific serine/threonine kinase family involved in the abscisic acid (ABA) signaling pathway and responds to osmotic stress. A genome-wide ...

    Authors: Zhao Liu, Xiaoyang Ge, Zuoren Yang, Chaojun Zhang, Ge Zhao, Eryong Chen, Ji Liu, Xueyan Zhang and Fuguang Li

    Citation: BMC Genetics 2017 18:54

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  25. Content type: Methodology article

    For the analysis of gene-environment (GxE) interactions commonly single nucleotide polymorphisms (SNPs) are used to characterize genetic susceptibility, an approach that mostly lacks power and has poor reprodu...

    Authors: Anke Hüls, Katja Ickstadt, Tamara Schikowski and Ursula Krämer

    Citation: BMC Genetics 2017 18:55

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    The Erratum to this article has been published in BMC Genetics 2017 18:73

  26. Content type: Research article

    The South West Indian Ocean (SWIO) archipelagos and Madagascar constitute a hotspot of biodiversity with a high rate of endemism. In this area, the endemic subspecies A. m. unicolor has been described in Madagasc...

    Authors: Maéva Angélique Techer, Johanna Clémencet, Christophe Simiand, Sookar Preeaduth, Hamza Abdou Azali, Bernard Reynaud and Delatte Hélène

    Citation: BMC Genetics 2017 18:53

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  27. Content type: Research article

    Mesencephalic Astrocyte-derived Neurotrophic Factor (MANF) and Cerebral Dopamine Neurotrophic Factor (CDNF) form an evolutionarily conserved family of neurotrophic factors. Orthologues for MANF/CDNF are the on...

    Authors: Riitta Lindström, Päivi Lindholm, Mari Palgi, Mart Saarma and Tapio I. Heino

    Citation: BMC Genetics 2017 18:52

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  28. Content type: Research Article

    The use of multiple genetic backgrounds across years is appealing for genomic prediction (GP) because past years’ data provide valuable information on marker effects. Nonetheless, single-year GP models are les...

    Authors: Angela-Maria Bernal-Vasquez, Andres Gordillo, Malthe Schmidt and Hans-Peter Piepho

    Citation: BMC Genetics 2017 18:51

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  29. Content type: Research article

    The structure of haplogroup H reveals significant differences between the western and eastern edges of the Mediterranean, as well as between the northern and southern regions. Human populations along the weste...

    Authors: Candela L. Hernández, Jean M. Dugoujon, Andrea Novelletto, Juan N. Rodríguez, Pedro Cuesta and Rosario Calderón

    Citation: BMC Genetics 2017 18:46

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  30. Content type: Research article

    Quantitative traits are common in nature, but quantitative pathogenicity has received only little attention in phytopathology. In this study, we used 100 Fusarium culmorum isolates collected from natural field en...

    Authors: Valheria Castiblanco, Jose J. Marulanda, Tobias Würschum and Thomas Miedaner

    Citation: BMC Genetics 2017 18:49

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  31. Content type: Research article

    Our previous RNA-sequencing study revealed that the ATF3 and CDKN1A genes were remarkably differentially expressed between the mammary glands of lactating Holstein cows with extremely high and low milk protein an...

    Authors: Bo Han, Weijun Liang, Lin Liu, Yanhua Li and Dongxiao Sun

    Citation: BMC Genetics 2017 18:47

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  32. Content type: Research article

    Differential plasma concentrations of circulating lipid species are associated with pathogenesis of type 2 diabetes (T2D). Whether the wide inter-individual variability in the plasma lipidome contributes to th...

    Authors: Hemant Kulkarni, Manju Mamtani, Gerard Wong, Jacquelyn M. Weir, Christopher K. Barlow, Thomas D. Dyer, Laura Almasy, Michael C. Mahaney, Anthony G. Comuzzie, Ravindranath Duggirala, Peter J. Meikle, John Blangero and Joanne E. Curran

    Citation: BMC Genetics 2017 18:48

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  33. Content type: Research article

    Due to the great advantages in selection accuracy and efficiency, genomic selection (GS) has been widely studied in livestock, crop and aquatic animals. Our previous study based on one full-sib family of Litopena...

    Authors: Quanchao Wang, Yang Yu, Jianbo Yuan, Xiaojun Zhang, Hao Huang, Fuhua Li and Jianhai Xiang

    Citation: BMC Genetics 2017 18:45

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  34. Content type: Methodology article

    Over the past decades, the prevalence of type 2 diabetes mellitus (T2D) has been steadily increasing around the world. Despite large efforts devoted to better understand the genetic basis of the disease, the i...

    Authors: Jie Ren, Tao He, Ye Li, Sai Liu, Yinhao Du, Yu Jiang and Cen Wu

    Citation: BMC Genetics 2017 18:44

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  35. Content type: Research article

    The SnRKs (sucrose non-fermenting 1 related protein kinase) are a gene family coding for Ser/Thr protein kinases and play important roles in linking the tolerance and metabolic responses of plants to abiotic s...

    Authors: Jiangping Bai, Juan Mao, Hongyu Yang, Awais Khan, Aqi Fan, Siyan Liu, Junlian Zhang, Di Wang, Huijuan Gao and Jinlin Zhang

    Citation: BMC Genetics 2017 18:41

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  36. Content type: Research article

    Naturally occurring mutations in growth and differentiation factor 9 (GDF9) or bone morphogenetic protein 15 (BMP15) genes are associated with increased ovulation rate (OR) and litter size (LS) but also sterility...

    Authors: Narjess Lassoued, Zohra Benkhlil, Florent Woloszyn, Ahmed Rejeb, Mohamed Aouina, Mourad Rekik, Stephane Fabre and Sonia Bedhiaf-Romdhani

    Citation: BMC Genetics 2017 18:43

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  37. Content type: Research article

    Two key questions in understanding the genetic control of behaviors are: what genes are involved and how these genes interact. To answer these questions at a systems level, we conducted high-content profiling of

    Authors: Boanerges Aleman-Meza, Mario Loeza-Cabrera, Omar Peña-Ramos, Michael Stern and Weiwei Zhong

    Citation: BMC Genetics 2017 18:40

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  38. Content type: Research article

    Oculocutaneous Albinism (OCA) is an autosomal recessive inherited condition that affects the pigmentation of eyes, hair and skin. The OCA phenotype may be caused by mutations in the tyrosinase gene (TYR), whic...

    Authors: Felipe Tadeu Galante Rocha de Vasconcelos, Einat Hauzman, Leonardo Dutra Henriques, Paulo Roney Kilpp Goulart, Olavo de Faria Galvão, Ronaldo Yuiti Sano, Givago da Silva Souza, Jessica Lynch Alfaro, Luis Carlos de Lima Silveira, Dora Fix Ventura and Daniela Maria Oliveira Bonci

    Citation: BMC Genetics 2017 18:39

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  39. Content type: Research article

    MicroRNAs (miRNAs) have a great influence on various physiological functions. A lot of high-throughput sequencing (HTS) research on miRNAs has been executed in the caprine mammary gland at different lactation ...

    Authors: Jinxing Hou, Xiaopeng An, Yuxuan Song, Binyun Cao, Heping Yang, Zhou Zhang, Wenzheng Shen and Yunpu Li

    Citation: BMC Genetics 2017 18:38

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  40. Content type: Research article

    The Elaeis oleifera genetic materials were assembled from its center of diversity in South and Central America. These materials are currently being preserved in Malaysia as ex situ living collections. Maintaining...

    Authors: Maizura Ithnin, Chee-Keng Teh and Wickneswari Ratnam

    Citation: BMC Genetics 2017 18:37

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  41. Content type: Research article

    Plant height (PH) and ear height (EH) are two important agronomic traits in maize selection breeding. F1 hybrid exhibit significant heterosis for PH and EH as compared to their parental inbred lines. To understan...

    Authors: Hongjian Li, Qingsong Yang, Nannan Fan, Ming Zhang, Huijie Zhai, Zhongfu Ni and Yirong Zhang

    Citation: BMC Genetics 2017 18:36

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  42. Content type: Research article

    Holocentric chromosomes occur in approximately 750 species of eukaryotes. Among them, the genus Tityus (Scorpiones, Buthidae) has a labile karyotype that shows complex multivalent associations during male meiosis...

    Authors: Bruno Rafael Ribeiro de Almeida, Susana Suely Rodrigues Milhomem-Paixão, Renata Coelho Rodrigues Noronha, Cleusa Yoshiko Nagamachi, Marlyson Jeremias Rodrigues da Costa, Pedro Pereira de Oliveira Pardal, Johne Souza Coelho and Julio Cesar Pieczarka

    Citation: BMC Genetics 2017 18:35

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  43. Content type: Research article

    The Atlantic salmon aquaculture industry is investigating the feasibility of using sterile triploids to mitigate genetic interactions with wild conspecifics, however, studies investigating diploid and triploid...

    Authors: A. C. Harvey, P. G. Fjelldal, M. F. Solberg, T. Hansen and K. A. Glover

    Citation: BMC Genetics 2017 18:34

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  44. Content type: Research article

    Auxin plays an important role in regulating plant growth and development as well as in the response of plants to abiotic stresses. Auxin is transported by three kinds of major protein families, including the A...

    Authors: Chenliang Yu, Wenqi Dong, Yihua Zhan, Zong-an Huang, Zhimiao Li, Il Seop Kim and Chenghao Zhang

    Citation: BMC Genetics 2017 18:33

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  45. Content type: Research article

    Genotyping-by-sequencing (GBS) has emerged as a powerful and cost-effective approach for discovering and genotyping single-nucleotide polymorphisms. The GBS technique was largely used in crop species where its...

    Authors: Jean-Simon Brouard, Brian Boyle, Eveline M. Ibeagha-Awemu and Nathalie Bissonnette

    Citation: BMC Genetics 2017 18:32

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  46. Content type: Research article

    Arabian horses are believed to be one of the oldest and most influential horse breeds in the world. Blood is the main tissue involved in maintaining body homeostasis, and it is considered a marker of the proce...

    Authors: Katarzyna Ropka-Molik, Monika Stefaniuk-Szmukier, Kacper Żukowski, Katarzyna Piórkowska, Artur Gurgul and Monika Bugno-Poniewierska

    Citation: BMC Genetics 2017 18:31

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