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Content type: Research article

Genetic modification of glaucoma associated phenotypes between AKXD-28/Ty and DBA/2J mice

Glaucoma is a common disease but its molecular etiology is poorly understood. It involves retinal ganglion cell death and optic nerve damage that is often associated with elevated intraocular pressure. Identif...

Authors: Michael G Anderson, Richard S Smith, Olga V Savinova, Norman L Hawes, Bo Chang, Adriana Zabaleta, Robert Wilpan, John R Heckenlively, Muriel Davisson and Simon WM John

Citation: BMC Genetics 2001 2:1

Published on: 15 January 2001
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Content type: Research article

Muscle Specific Fragile X Related Protein 1 Isoforms are Sequestered in the Nucleus of Undifferentiated Myoblast

The family of Fragile X Mental Retardation Proteins is composed of three members: Fragile Mental Retardation 1, Fragile X Related 1 and X Related 2 proteins. These proteins are associated with mRNPs within tra...

Authors: Marthe Dubé, Marc-Etienne Huot and Edouard W Khandjian

Citation: BMC Genetics 2000 1:4

Published on: 7 December 2000
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Content type: Research article

In vivo labelling of functional ribosomes reveals spatial regulation during starvation in Podospora anserina

To date, in eukaryotes, ribosomal protein expression is known to be regulated at the transcriptional and/or translational levels. But other forms of regulation may be possible.

Authors: Hervé Lalucque and Philippe Silar

Citation: BMC Genetics 2000 1:3

Published on: 16 November 2000
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Content type: Research article

Hepatic glucokinase promoter polymorphism is associated with hepatic insulin resistance in Asian Indians.

The role of glucokinase (GCK) in the pathogenesis of maturity-onset diabetes of the young is well established. However, its role in the common form of type 2 diabetes is far from convincing. We investigated th...

Authors: Ken C Chiu, Lee-Ming Chuang, Carol Yoon and Mohammad F Saad

Citation: BMC Genetics 2000 1:2

Published on: 16 November 2000
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Content type: Research article

Human cytomegalovirus IE1 promoter/enhancer drives variable gene expression in all fiber types in transgenic mouse skeletal muscle

Versatile transgenic manipulation of skeletal muscle requires knowledge of the expression profiles of diverse promoter/enhancer elements in the transcriptionally specialized fiber types of which muscle is comp...

Authors: Patricia L. Hallauer and Kenneth E.M. Hastings

Citation: BMC Genetics 2000 1:1

Published on: 4 October 2000
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Articles

Genetic modification of glaucoma associated phenotypes between AKXD-28/Ty and DBA/2J mice

Muscle Specific Fragile X Related Protein 1 Isoforms are Sequestered in the Nucleus of Undifferentiated Myoblast

In vivo labelling of functional ribosomes reveals spatial regulation during starvation in Podospora anserina

Hepatic glucokinase promoter polymorphism is associated with hepatic insulin resistance in Asian Indians.

Human cytomegalovirus IE1 promoter/enhancer drives variable gene expression in all fiber types in transgenic mouse skeletal muscle

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