2 affected sibs | 3 affected sibs | 4 affected sibs | ||||||
---|---|---|---|---|---|---|---|---|
Method | LD threshold | Ave # SNPs | MLS (SD) | IC | MLS (SD) | IC | MLS (SD) | IC |
Unadjusted | 3713 | 9.62 (2.75) | 0.72 | 14.01 (3.43) | 0.80 | 5.02 (1.95) | 0.85 | |
RE | 0.7 | 1562 | 1.39 (0.98) | 0.73 | 2.00 (1.28) | 0.80 | 0.73 (0.70) | 0.85 |
RE | 0.5 | 1240 | 1.21 (0.90) | 0.73 | 1.67 (1.17) | 0.81 | 0.59 (0.63) | 0.85 |
RE | 0.3 | 892 | 0.45 (0.53) | 0.73 | 0.66 (0.68) | 0.81 | 0.26 (0.39) | 0.85 |
RE | 0.1 | 435 | 0.32 (0.44) | 0.72 | 0.40 (0.49) | 0.80 | 0.18 (0.34) | 0.85 |
MERLINLD | 0.7 | 562 | 1.35 (0.97) | 0.73 | 1.83 (1.22) | 0.80 | 0.62 (0.61) | 0.85 |
MERLINLD | 0.5 | 575 | 1.12 (0.96) | 0.73 | 1.53 (1.19) | 0.80 | 0.53 (0.59) | 0.85 |
MERLINLD | 0.3 | 542 | 0.55 (0.61) | 0.74 | 0.77 (0.77) | 0.80 | 0.32 (0.43) | 0.85 |
MERLINLD | 0.1 | 423 | 0.51 (0.58) | 0.74 | 0.69 (0.70) | 0.81 | 0.29 (0.41) | 0.85 |
SNPLINK | 0.7 | 2596 | 3.94 (1.85) | 0.73 | 5.10 (2.11) | 0.80 | 2.06 (1.23) | 0.85 |
SNPLINK | 0.5 | 2351 | 3.63 (1.81) | 0.73 | 4.88 (2.09) | 0.80 | 1.97 (1.20) | 0.85 |
SNPLINK | 0.3 | 2057 | 3.04 (1.73) | 0.73 | 4.10 (1.95) | 0.80 | 1.56 (1.07) | 0.85 |
SNPLINK | 0.1 | 1519 | 2.69 (1.64) | 0.73 | 3.57 (1.87) | 0.80 | 1.28 (0.98) | 0.85 |