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  1. Research article

    Genetic correlation of the plasma lipidome with type 2 diabetes, prediabetes and insulin resistance in Mexican American families

    Differential plasma concentrations of circulating lipid species are associated with pathogenesis of type 2 diabetes (T2D). Whether the wide inter-individual variability in the plasma lipidome contributes to th...

    Hemant Kulkarni, Manju Mamtani, Gerard Wong, Jacquelyn M. Weir, Christopher K. Barlow, Thomas D. Dyer, Laura Almasy, Michael C. Mahaney, Anthony G. Comuzzie, Ravindranath Duggirala, Peter J. Meikle, John Blangero and Joanne E. Curran

    BMC Genetics 2017 18:48

    Published on: 19 May 2017

  2. Research article

    Candidate gene based association mapping in Fusarium culmorum for field quantitative pathogenicity and mycotoxin production in wheat

    Quantitative traits are common in nature, but quantitative pathogenicity has received only little attention in phytopathology. In this study, we used 100 Fusarium culmorum isolates collected from natural field en...

    Valheria Castiblanco, Jose J. Marulanda, Tobias Würschum and Thomas Miedaner

    BMC Genetics 2017 18:49

    Published on: 19 May 2017

  3. Research article

    The distribution of mitochondrial DNA haplogroup H in southern Iberia indicates ancient human genetic exchanges along the western edge of the Mediterranean

    The structure of haplogroup H reveals significant differences between the western and eastern edges of the Mediterranean, as well as between the northern and southern regions. Human populations along the weste...

    Candela L. Hernández, Jean M. Dugoujon, Andrea Novelletto, Juan N. Rodríguez, Pedro Cuesta and Rosario Calderón

    BMC Genetics 2017 18:46

    Published on: 19 May 2017

  4. Research article

    Effects of marker density and population structure on the genomic prediction accuracy for growth trait in Pacific white shrimp Litopenaeus vannamei

    Due to the great advantages in selection accuracy and efficiency, genomic selection (GS) has been widely studied in livestock, crop and aquatic animals. Our previous study based on one full-sib family of Litopena...

    Quanchao Wang, Yang Yu, Jianbo Yuan, Xiaojun Zhang, Hao Huang, Fuhua Li and Jianhai Xiang

    BMC Genetics 2017 18:45

    Published on: 17 May 2017

  5. Research article

    FecX Bar a Novel BMP15 mutation responsible for prolificacy and female sterility in Tunisian Barbarine Sheep

    Naturally occurring mutations in growth and differentiation factor 9 (GDF9) or bone morphogenetic protein 15 (BMP15) genes are associated with increased ovulation rate (OR) and litter size (LS) but also sterility...

    Narjess Lassoued, Zohra Benkhlil, Florent Woloszyn, Ahmed Rejeb, Mohamed Aouina, Mourad Rekik, Stephane Fabre and Sonia Bedhiaf-Romdhani

    BMC Genetics 2017 18:43

    Published on: 15 May 2017

  6. Research article

    Sucrose non-ferment 1 related protein kinase 2 (SnRK2) genes could mediate the stress responses in potato (Solanum tuberosum L.)

    The SnRKs (sucrose non-fermenting 1 related protein kinase) are a gene family coding for Ser/Thr protein kinases and play important roles in linking the tolerance and metabolic responses of plants to abiotic s...

    Jiangping Bai, Juan Mao, Hongyu Yang, Awais Khan, Aqi Fan, Siyan Liu, Junlian Zhang, Di Wang, Huijuan Gao and Jinlin Zhang

    BMC Genetics 2017 18:41

    Published on: 15 May 2017

  7. Research article

    High-content behavioral profiling reveals neuronal genetic network modulating Drosophila larval locomotor program

    Two key questions in understanding the genetic control of behaviors are: what genes are involved and how these genes interact. To answer these questions at a systems level, we conducted high-content profiling of

    Boanerges Aleman-Meza, Mario Loeza-Cabrera, Omar Peña-Ramos, Michael Stern and Weiwei Zhong

    BMC Genetics 2017 18:40

    Published on: 12 May 2017

  8. Research article

    A novel nonsense mutation in the tyrosinase gene is related to the albinism in a capuchin monkey (Sapajus apella)

    Oculocutaneous Albinism (OCA) is an autosomal recessive inherited condition that affects the pigmentation of eyes, hair and skin. The OCA phenotype may be caused by mutations in the tyrosinase gene (TYR), whic...

    Felipe Tadeu Galante Rocha de Vasconcelos, Einat Hauzman, Leonardo Dutra Henriques, Paulo Roney Kilpp Goulart, Olavo de Faria Galvão, Ronaldo Yuiti Sano, Givago da Silva Souza, Jessica Lynch Alfaro, Luis Carlos de Lima Silveira, Dora Fix Ventura and Daniela Maria Oliveira Bonci

    BMC Genetics 2017 18:39

    Published on: 5 May 2017

  9. Research article

    Detection and comparison of microRNAs in the caprine mammary gland tissues of colostrum and common milk stages

    MicroRNAs (miRNAs) have a great influence on various physiological functions. A lot of high-throughput sequencing (HTS) research on miRNAs has been executed in the caprine mammary gland at different lactation ...

    Jinxing Hou, Xiaopeng An, Yuxuan Song, Binyun Cao, Heping Yang, Zhou Zhang, Wenzheng Shen and Yunpu Li

    BMC Genetics 2017 18:38

    Published on: 2 May 2017

  10. Research article

    Karyotype diversity and chromosomal organization of repetitive DNA in Tityus obscurus (Scorpiones, Buthidae)

    Holocentric chromosomes occur in approximately 750 species of eukaryotes. Among them, the genus Tityus (Scorpiones, Buthidae) has a labile karyotype that shows complex multivalent associations during male meiosis...

    Bruno Rafael Ribeiro de Almeida, Susana Suely Rodrigues Milhomem-Paixão, Renata Coelho Rodrigues Noronha, Cleusa Yoshiko Nagamachi, Marlyson Jeremias Rodrigues da Costa, Pedro Pereira de Oliveira Pardal, Johne Souza Coelho and Julio Cesar Pieczarka

    BMC Genetics 2017 18:35

    Published on: 17 April 2017

  11. Research article

    Quantitative trait locus analysis of heterosis for plant height and ear height in an elite maize hybrid zhengdan 958 by design III

    Plant height (PH) and ear height (EH) are two important agronomic traits in maize selection breeding. F1 hybrid exhibit significant heterosis for PH and EH as compared to their parental inbred lines. To understan...

    Hongjian Li, Qingsong Yang, Nannan Fan, Ming Zhang, Huijie Zhai, Zhongfu Ni and Yirong Zhang

    BMC Genetics 2017 18:36

    Published on: 17 April 2017

  12. Research article

    Ploidy elicits a whole-genome dosage effect: growth of triploid Atlantic salmon is linked to the genetic origin of the second maternal chromosome set

    The Atlantic salmon aquaculture industry is investigating the feasibility of using sterile triploids to mitigate genetic interactions with wild conspecifics, however, studies investigating diploid and triploid...

    A. C. Harvey, P. G. Fjelldal, M. F. Solberg, T. Hansen and K. A. Glover

    BMC Genetics 2017 18:34

    Published on: 11 April 2017

  13. Research article

    Genome-wide identification and expression analysis of ClLAX, ClPIN and ClABCB genes families in Citrullus lanatus under various abiotic stresses and grafting

    Auxin plays an important role in regulating plant growth and development as well as in the response of plants to abiotic stresses. Auxin is transported by three kinds of major protein families, including the A...

    Chenliang Yu, Wenqi Dong, Yihua Zhan, Zong-an Huang, Zhimiao Li, Il Seop Kim and Chenghao Zhang

    BMC Genetics 2017 18:33

    Published on: 7 April 2017

  14. Research article

    Transcriptome profiling of Arabian horse blood during training regimens

    Arabian horses are believed to be one of the oldest and most influential horse breeds in the world. Blood is the main tissue involved in maintaining body homeostasis, and it is considered a marker of the proce...

    Katarzyna Ropka-Molik, Monika Stefaniuk-Szmukier, Kacper Żukowski, Katarzyna Piórkowska, Artur Gurgul and Monika Bugno-Poniewierska

    BMC Genetics 2017 18:31

    Published on: 5 April 2017

  15. Research article

    Low-depth genotyping-by-sequencing (GBS) in a bovine population: strategies to maximize the selection of high quality genotypes and the accuracy of imputation

    Genotyping-by-sequencing (GBS) has emerged as a powerful and cost-effective approach for discovering and genotyping single-nucleotide polymorphisms. The GBS technique was largely used in crop species where its...

    Jean-Simon Brouard, Brian Boyle, Eveline M. Ibeagha-Awemu and Nathalie Bissonnette

    BMC Genetics 2017 18:32

    Published on: 5 April 2017

  16. Research article

    A genome-wide association study reveals a locus for bilateral iridal hypopigmentation in Holstein Friesian cattle

    Eye pigmentation abnormalities in cattle are often related to albinism, Chediak-Higashi or Tietz like syndrome. However, mutations only affecting pigmentation of coat color and eye have also been described. He...

    Anne K. Hollmann, Martina Bleyer, Andrea Tipold, Jasmin N. Neßler, Wilhelm E. Wemheuer, Ekkehard Schütz and Bertram Brenig

    BMC Genetics 2017 18:30

    Published on: 29 March 2017

  17. Research article

    Genomic regions underlying susceptibility to bovine tuberculosis in Holstein-Friesian cattle

    The significant social and economic loss as a result of bovine tuberculosis (bTB) presents a continuous challenge to cattle industries in the UK and worldwide. However, host genetic variation in cattle suscept...

    Kethusegile Raphaka, Oswald Matika, Enrique Sánchez-Molano, Raphael Mrode, Mike Peter Coffey, Valentina Riggio, Elizabeth Janet Glass, John Arthur Woolliams, Stephen Christopher Bishop and Georgios Banos

    BMC Genetics 2017 18:27

    Published on: 23 March 2017

  18. Research article

    The patterns of genomic variances and covariances across genome for milk production traits between Chinese and Nordic Holstein populations

    With the development of SNP chips, SNP information provides an efficient approach to further disentangle different patterns of genomic variances and covariances across the genome for traits of interest. Due to...

    Xiujin Li, Mogens Sandø Lund, Luc Janss, Chonglong Wang, Xiangdong Ding, Qin Zhang and Guosheng Su

    BMC Genetics 2017 18:26

    Published on: 15 March 2017

  19. Research article

    Genetic diversity of a New Zealand multi-breed sheep population and composite breeds’ history revealed by a high-density SNP chip

    Knowledge about the genetic diversity of a population is a crucial parameter for the implementation of successful genomic selection and conservation of genetic resources. The aim of this research was to establ...

    Luiz F. Brito, John C. McEwan, Stephen P. Miller, Natalie K. Pickering, Wendy E. Bain, Ken G. Dodds, Flávio S. Schenkel and Shannon M. Clarke

    BMC Genetics 2017 18:25

    Published on: 14 March 2017

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