Figure 1From: Confirmation of warfarin resistance of naturally occurring VKORC1 variants by coexpression with coagulation factor IX and in silico protein modelling Specific activities of coagulation factor IX coexpressed with different VKORC1 variants: wild-type (= 100%) and (A): N-terminal variants at positions 12, 56, 59, 61, 63 and 67; (B): C-terminal variants at positions 120, 128 and 139 in the absence and presence of different warfarin concentrations. Back to article page