Genetic fixity in the human major histocompatibility complex and block size diversity in the class I region including HLA-E

Romero, Viviana; Larsen, Charles E; Duke-Cohan, Jonathan S; Fox, Edward A; Romero, Tatiana; Clavijo, Olga P; Fici, Dolores A; Husain, Zaheed; Almeciga, Ingrid; Alford, Dennis R; Awdeh, Zuheir L; Zuñiga, Joaquin; El-Dahdah, Lama; Alper, Chester A; Yunis, Edmond J

doi:10.1186/1471-2156-8-14

Table 2 Statistical analysis of HLA-A, -E, -Cw and -B haplotypes for Panel 3.

From: Genetic fixity in the human major histocompatibility complex and block size diversity in the class I region including HLA-E

HLA-A*	HLA-E*	f	p	HLA-E*	HLA-Cw/B	f	p	HLA-A*	HLA-E*	HLA-Cw/B	f	p
01	*0101*	61/258	< 1 × 10^-7	*0101*	*07, 08*	49/258	9 × 10^-6	01	*0101*	*07, 08*	44/258	< 1 × 10^-7
				*0101*	*06, 57*	12/258	ns	01	*0101*	*06, 57*	10/258	5 × 10^-5
02	*0101*	34/258	ns	*0101*	*07, 07*	10/258	ns	02	*0101*	*07,07*	7/258	0.007
				*0101*	*05, 44*	9/258	ns	02	*0101*	*05, 44*	8/258	0.00013
				*0101*	*06, 50*	6/258	ns	02	*0101*	*06, 50*	3/258	ns
02	*010302*	15/258	ns	*010302*	*03,15*	2/258	ns	02	*010302*	*03,15*	3/258	ns
03	*0101*	6/258	ns	*0101*	*06, 47*	2/258	ns	03	*0101*	*06, 47*	2/258	ns
03	*010302*	16/258	3 × 10^-5	*010302*	*07, 07*	18/258	0.00046	03	*010302*	*07, 07*	14/258	< 1 × 10^-7
11	*0101*	9/258	ns	*0101*	*04, 35*	7/258	ns	11	*0101*	*04, 35*	4/258	0.0006
23	*0101*	10/258	ns	*0101*	*04, 44*	9/258	ns	23	*0101*	*04, 44*	7/258	< 1 × 10^-7
24	*0101*	10/258	ns	*0101*	*08, 14*	7/258	ns	23	*0101*	*08, 14*	1/258	ns
25	*0101*	5/258	ns	*0101*	*12, 18*	8/258	ns	25	*0101*	*12, 18*	5/258	< 1 × 10^-7
26	*010301*	16/258	< 1 × 10^-7	*010301*	*12, 38*	14/258	< 1 × 10^-7	26	*010301*	*12, 38*	14/258	< 1 × 10^-7
29	*010302*	17/258	9 × 10^-7	*010302*	*16, 44*	16/258	< 1 × 10^-7	29	*010302*	*16, 44*	16/258	< 1 × 10^-7
30	*0101*	6/258	ns	*0101*	*06, 13*	5/258	ns	30	*0101*	*06, 13*	4/258	0.00063
30	*010302*	10/258	0.0261	*010302*	*05,18*	12/258	0.0002	30	*010302*	*05,18*	10/258	< 1 × 10^-7
33	*0101*	4/258	ns	*0101*	*03, 58*	3/258	ns	33	*0101*	*03, 58*	2/258	0.009

¹Frequency (f)
²Probability (p)
Not significant (ns)

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