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Figure 4 | BMC Genetics

Figure 4

From: Robust physical methods that enrich genomic regions identical by descent for linkage studies: confirmation of a locus for osteogenesis imperfecta

Figure 4

Quantitative PCR detects an extensive range of enrichment of IBD DNA. Eight CA microsatellite sites were assayed by qPCR using a universal (CA)n-specific probe and IBD-enriched DNA from complementary grandparent-grandchild pairs. Loci 1–4 represent shared loci for the grandfather-grandchild pair and loci 5–8 represent shared loci for the grandmother-grandchild pair. Ct is the cycle number at which a common threshold level of amplification was achieved.

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