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Table 7 Epistatic model - mixed (EPI RD).

From: Neural networks for modeling gene-gene interactions in association studies

 

Low risk

High risk

 

r1 = 2; r2 = 4

r1 = 5; r2 = 10

Theoretical penetrance matrix

Neural network

  

   Mean absolute difference E

   Sum

0.2239

0.1563

Logistic regression

  

   Mean absolute difference E

   Sum

0.5105

0.8658

Logistic regression (design variables)

  

   Mean absolute difference E

   Sum

0.2799

0.2329

  1. Mean absolute differences between theoretical and estimated penetrance matrices from 100 replications in the low and high risk scenario.
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