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Table 2 Obesity traits in five subcongenics and their parental strains on low-fat standard chow diet

From: A wild derived quantitative trait locus on mouse chromosome 2 prevents obesity

Sex Strain n Body weight (g) Lean body weight (g) Inguinal fat pad weight (g) Gonadal fat pad weight (g) Retroperitoneal fat pad weight (g) Total fat pad weight (g) Adiposity index
Male B6 45 27.28 ± 0.051 26.23 ± 0.048 0.455 ± 0.005 0.424 ± 0.003 0.164 ± 0.003 1.043 ± 0.009 0.038 ± 0.0003
  B6.Cg-Pbwg1 40 26.83 ± 0.063 26.04 ± 0.061 0.336 ± 0.003*** 0.338 ± 0.003*** 0.116 ± 0.002*** 0.790 ± 0.004*** 0.031 ± 0.0007***
  B6.Cg-Pbwg1/SR13 15 27.69 ± 0.057 26.90 ± 0.056 0.345 ± 0.006** 0.308 ± 0.006*** 0.132 ± 0.004 0.785 ± 0.014*** 0.035 ± 0.0008***
  B6.Cg-Pbwg1/SR12 30 29.00 ± 0.115** 28.07 ± 0.108** 0.393 ± 0.007* 0.390 ± 0.007 0.149 ± 0.003 0.933 ± 0.014* 0.028 ± 0.0008***
  B6.Cg-Pbwg1/SR8 39 26.13 ± 0.055* 25.49 ± 0.054* 0.293 ± 0.004*** 0.265 ± 0.003*** 0.082 ± 0.002*** 0.641 ± 0.007*** 0.030 ± 0.0014***
  B6.Cg-Pbwg1/SR3 16 27.22 ± 0.039 26.19 ± 0.036 0.439 ± 0.003 0.453 ± 0.003 0.176 ± 0.004 1.029 ± 0.009 0.031 ± 0.0001
  B6.Cg-Pbwg1/SR4 23 28.01 ± 0.172 26.89 ± 0.157 0.466 ± 0.011 0.470 ± 0.006 0.191 ± 0.007 1.128 ± 0.022 0.034 ± 0.0011
Female B6 39 21.96 ± 0.044 21.17 ± 0.043 0.359 ± 0.002 0.296 ± 0.002 0.136 ± 0.001 0.791 ± 0.003 0.036 ± 0.0002
  B6.Cg-Pbwg1 31 21.24 ± 0.056** 20.63 ± 0.052** 0.266 ± 0.002*** 0.234 ± 0.002*** 0.108 ± 0.001*** 0.608 ± 0.004*** 0.029 ± 0.0002***
  B6.Cg-Pbwg1/SR13 14 21.03 ± 0.055 20.48 ± 0.053 0.268 ± 0.001*** 0.175 ± 0.003*** 0.104 ± 0.001* 0.547 ± 0.005*** 0.026 ± 0.0003***
  B6.Cg-Pbwg1/SR12 30 22.33 ± 0.066 21.55 ± 0.061 0.366 ± 0.003 0.278 ± 0.004 0.130 ± 0.002 0.774 ± 0.005 0.034 ± 0.0002
  B6.Cg-Pbwg1/SR8 31 20.02 ± 0.050*** 19.59 ± 0.049*** 0.233 ± 0.003*** 0.129 ± 0.002*** 0.063 ± 0.001*** 0.425 ± 0.004*** 0.021 ± 0.0002***
  B6.Cg-Pbwg1/SR3 14 21.81 ± 0.066 21.12 ± 0.067 0.344 ± 0.002 0.289 ± 0.002 0.147 ± 0.001 0.780 ± 0.005 0.036 ± 0.0003
  B6.Cg-Pbwg1/SR4 27 22.14 ± 0.046 21.36 ± 0.041 0.375 ± 0.005 0.288 ± 0.005 0.112 ± 0.002* 0.776 ± 0.006 0.035 ± 0.0002
  1. Data are least-squared means ± SE at 13 weeks of age. n, number of mice. Sex separated data were analyzed with a linear mixed model (see Materials and Methods) and fat pad weights were not adjusted for lean body weight. Total fat pad weight is the sum of the three fat pad weights. Adiposity index was calculated by dividing total fat pad weight by body weight. The mean with stars (*, P < 0.05; **, P < 0.01; ***, P < 0.001) within the same sex is significantly different from that of B6 (Dunnett's test).