A wild derived quantitative trait locus on mouse chromosome 2 prevents obesity

BMC Genomic Data

Table 3 Obesity traits in selected subcongenics and their parental strains on high-fat diet

Strain	n	Body weight (g)	Lean body weight (g)	Inguinal fat pad weight (g)	Gonadal fat pad weight (g)	Retroperitoneal fat pad weight (g)	Total fat pad weight (g)	Adiposity index
B6	15	32.318 ± 0.165	29.21 ± 0.127	1.203 ± 0.024	1.294 ± 0.039	0.604 ± 0.021	3.100 ± 0.083	0.093 ± 0.002
B6.Cg-Pbwg1	12	29.752 ± 0.047*	28.01 ± 0.149	0.625 ± 0.023***	0.794 ± 0.037***	0.327 ± 0.020**	1.745 ± 0.081***	0.058 ± 0.002***
B6.Cg-Pbwg1/SR12	11	34.028 ± 0.149	30.44 ± 0.133	1.495 ± 0.019*	1.418 ± 0.013*	0.673 ± 0.011	3.586 ± 0.044	0.105 ± 0.001
B6.Cg-Pbwg1/SR8	13	28.058 ± 0.186**	26.84 ± 0.147*	0.478 ± 0.034***	0.547 ± 0.043***	0.196 ± 0.025***	1.221 ± 0.098***	0.043 ± 0.003***
B6.Cg-Pbwg1/SR4	10	31.861 ± 0.234	28.89 ± 0.145	1.134 ± 0.033	1.274 ± 0.052	0.563 ± 0.027	2.970 ± 0.112	0.092 ± 0.003

Data are least-squared means ± SE at 13 weeks of age. n, number of mice. Data were analyzed with a linear model (see Materials and Methods) and fat pad weights were not adjusted for lean body weight. Total fat pad weight is the sum of the three fat pad weights. Adiposity index was calculated by dividing total fat pad weight by body weight. The mean with stars (*, P < 0.05; **, P < 0.01; ***, P < 0.001) within the same sex is significantly different from that of B6 (Dunnett's test).

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