Skip to main content

Table 3 Obesity traits in selected subcongenics and their parental strains on high-fat diet

From: A wild derived quantitative trait locus on mouse chromosome 2 prevents obesity

Strain n Body weight (g) Lean body weight (g) Inguinal fat pad weight (g) Gonadal fat pad weight (g) Retroperitoneal fat pad weight (g) Total fat pad weight (g) Adiposity index
B6 15 32.318 ± 0.165 29.21 ± 0.127 1.203 ± 0.024 1.294 ± 0.039 0.604 ± 0.021 3.100 ± 0.083 0.093 ± 0.002
B6.Cg-Pbwg1 12 29.752 ± 0.047* 28.01 ± 0.149 0.625 ± 0.023*** 0.794 ± 0.037*** 0.327 ± 0.020** 1.745 ± 0.081*** 0.058 ± 0.002***
B6.Cg-Pbwg1/SR12 11 34.028 ± 0.149 30.44 ± 0.133 1.495 ± 0.019* 1.418 ± 0.013* 0.673 ± 0.011 3.586 ± 0.044 0.105 ± 0.001
B6.Cg-Pbwg1/SR8 13 28.058 ± 0.186** 26.84 ± 0.147* 0.478 ± 0.034*** 0.547 ± 0.043*** 0.196 ± 0.025*** 1.221 ± 0.098*** 0.043 ± 0.003***
B6.Cg-Pbwg1/SR4 10 31.861 ± 0.234 28.89 ± 0.145 1.134 ± 0.033 1.274 ± 0.052 0.563 ± 0.027 2.970 ± 0.112 0.092 ± 0.003
  1. Data are least-squared means ± SE at 13 weeks of age. n, number of mice. Data were analyzed with a linear model (see Materials and Methods) and fat pad weights were not adjusted for lean body weight. Total fat pad weight is the sum of the three fat pad weights. Adiposity index was calculated by dividing total fat pad weight by body weight. The mean with stars (*, P < 0.05; **, P < 0.01; ***, P < 0.001) within the same sex is significantly different from that of B6 (Dunnett's test).