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Table 2 Genotypic and allelic frequency of NAT2 gene in different ethnic groups.

From: Interethnic diversity of NAT2 polymorphisms in Brazilian admixed populations

NAT2
SNP
Total Afro-Brazilians χ 2 p 1 Whites χ 2 p 2 Amerindians χ 2 p 3
G191A
GG 158 104    23    27   
GA 22 20 1.075 0.5842 4 1.781 0.4104 3 1.207 0.547
AA 3 1    1    0   
G 28 228 0.202 0.6593 50 1.322 0.2471 57 0.942 0.3061
A 338 22    6    3   
C481T
CC 72 41    11    12   
CT 79 60 2.565 0.2774 15 4.836 0.089 10 2.36 0.3073
TT 31 23    2    8   
C 223 142 1.466 0.2221 37 1.079 0.2982 34 0.007 0.9338
T 141 106    19    26   
G590A
GG 92 77    19    10   
GA 67 46 1.298 0.5224 8 4.312 0.1158 14 9.943 0.0069 b
AA 24 2    1    6   
G 251 200 0.005 0.9405 46 4.661 0.0288 a 34 8.4 0.0053 c
A 115 50    10    26   
A803G
AA 107 64    15    17   
AG 73 61 3.662 0.1603 11 1.333 0.5135 12 0.954 0.6207
GG 3 0    2    1   
A 287 189 1.686 0.1836 41 0.117 0.7316 46 0.834 0.3538
G 79 61    15    14   
G857A
GG 129 86    17    24   
GA 51 33 0.986 0.6108 10 3.391 0.1835 6 3.244 0.1975
AA 3 6    1    0   
G 309 205 0.419 0.524 44 2.750 0.0964 54 2.013 0.1373
A 57 45    12    6   
  1. p: Genotype and allelic p-value for each marker, respectively. p1, p2and p3: Association between Afro-Brazilians × Whites; Whites × Amerindians and Amerindians × Afro-Brazilians, respectively. a, b and c: p-value adjusted (103 permutations) = 0.06494, 0.006993 and 0.004995, respectively. χ2: Chi-square tests. Significant association is indicated in bold.