Table 3 Genotype distributions, odds ratios (OR), and their 95% confidence intervals (CI) and p-values for the genetic models
From: Genetic predisposition for femoral neck stress fractures in military conscripts
p-value | |||||||||
|---|---|---|---|---|---|---|---|---|---|
Gene | SNPs ID | Genotype | Counts (Controls/Cases) | OR | 95% CI | General association | Dominant | Additive | Recessive |
VDR | rs10735810 | C/C | 41/29 | 1 | 0.24 | 0.57 | 0.80 | 0.18 | |
T/C | 58/30 | 0.71 | 0.38-1.35 | ||||||
T/T | 11/10 | 1.50 | 0.60-3.78 | ||||||
rs1544410 | G/G | 46/17 | 1 | 0.15 | 0.08 | 0.22 | 0.91 | ||
G/A | 58/25 | 0.54 | 0.28-1.01 | ||||||
A/A | 16/10 | 0.78 | 0.32-1.91 | ||||||
rs731236 | T/T | 49/37 | 1 | 0.32 | 0.15 | 0.30 | 0.96 | ||
T/C | 54/25 | 0.61 | 0.32-1.16 | ||||||
C/C | 17/10 | 0.78 | 0.32-1.90 | ||||||
IL6 | rs1800795 | G/G | 35/15 | 1 | 0.27 | 0.20 | 0.63 | 0.59 | |
G/C | 56/42 | 1.75 | 0.85-3.61 | ||||||
C/C | 29/15 | 1.21 | 0.51-2.88 | ||||||
CTR | rs1922295 | T/T | 59/45 | 1 | 0.12 | 0.07 | 0.22 | 0.81 | |
T/C | 49/19 | 0.51 | 0.25-0.98 | ||||||
C/C | 12/8 | 0.87 | 0.33-2.32 | ||||||
COL1A1 | rs1800012 | G/G | 85/53 | 1 | 0.48 | 0.68 | 0.91 | 0.30 | |
G/T | 34/17 | 0.80 | 0.41-1.58 | ||||||
T/T | 1/2 | 3.21 | 0.28-36.25 | ||||||
rs2696247 | T/T | 189/100 | 1 | 0.45 | - | - | - | ||
T/C | 123/88 | 1.27 | 0.68-2.35 | ||||||
rs2586488 | C/C | 50/30 | 1 | 0.09 | 1.0 | 0.30 | 0.04 1 | ||
C/T | 58/27 | 0.78 | 0.41-1.48 | ||||||
T/T | 12/15 | 2.08 | 0.86-5.04 | ||||||
COL1A2 | rs406226 | A/A | 86/50 | 1 | 0.14 | 0.74 | 0.49 | - | |
A/G | 34/20 | 1.01 | 0.53-1.94 | ||||||
G/G | 0/2 | - | - | ||||||
rs2301643 | G/G | 88/50 | 1 | 0.13 | 0.56 | 0.35 | - | ||
G/A | 32/20 | 1.10 | 0.57-2.12 | ||||||
A/A | 0/2 | - | - | ||||||
rs3216902 | Ins/Ins | 52/29 | 1 | 0.05 | 0.68 | 0.46 | 0.03 2 | ||
Ins/NoI | 47/38 | 1.45 | 0.78-2.71 | ||||||
NoI/NoI | 21/5 | 0.43 | 0.15-1.25 | ||||||
LRP5 | rs2277268 | G/G | 111/59 | 1 | 0.03 | - | - | - | |
G/A | 9/13 | 2.72 | 1.10-6.73 | ||||||
rs4988321 | G/G | 115/65 | 1 | 0.13 | - | - | - | ||
G/A | 5/7 | 2.48 | 0.76-8.12 | ||||||
rs556442 | A/A | 82/43 | 1 | 0.36 | 0.23 | 0.17 | 0.30 | ||
A/G | 36/26 | 1.38 | 0.74-2.57 | ||||||
G/G | 2/3 | 2.86 | 0.46-17.78 | ||||||
rs3736228 | C/C | 107/62 | 1 | 0.53 | - | - | - | ||
C/T | 13/100 | 1.33 | 0.55-3.21 | ||||||