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Table 2 Associations of the SNPs and haplotypes in ESR 2, EAAT 2, BDNF, GABRA 6, DRD 1, OXTR and 5-HTR2C genes with sow maternal infanticide behavior

From: Association and haplotype analysis of candidate genes in five genomic regions linked to sow maternal infanticide in a white Duroc × Erhualian resource population

gene Polymorphism Allele or Haplotype1 Allele or Haplotype Frequency Individuals of maternal infanticide
     T UT DF LRS P
ESR 2 (HM754215) g.1170 G > A A 0.341 40 24 1 4.043 0.044*
   G 0.659 24 40    
  g. 1202G > A A 0.501 52 29 1 6.623 0.010*
   G 0.499 29 52    
  g. 2681G > T G 0.534 50 28 1 6.290 0.012*
   T 0.466 28 50    
  - GGT 0.457 10 30 2 5.993 0.049*
  - GAG 0.143 7 2    
  - AAG 0.361 23 8    
EAAT 2 (HM754214) g. 233G > A A 0.693 43 20 1 8.594 0.003*
   G 0.307 20 43    
  g.489G > A A 0.235 19 28 1 1.734 0.188
   G 0.765 28 19    
  g.1028G > A A 0.238 20 29 1 1.662 0.197
   G 0.762 29 20    
  - AGG 0.652 29 6 2 10.124 0.007*
  - GAA 0.278 4 20    
  - GGG 0.070 2 11    
BDNF (HM754212) g.612C > A C 0.748 27 19 1 1.391 0.238
   A 0.252 19 27    
  g.2723G > A G 0.513 37 45 1 0.781 0.377
   A 0.487 45 37    
  g.3481A > G A 0.594 33 31 1 0.063 0.803
   G 0.406 31 33    
  - AAA 0.245 9 12 3 3.762 0.288
  - CAA 0.241 19 8    
  - CGA 0.108 4 9    
  - CGG 0.394 16 19    
OXTR (HM754217) g.509G > A G 0.811 21 15 1 1.000 0.316
   A 0.189 15 21    
  g.1211T > C T 0.487 26 35 1 1.333 0.248
   C 0.513 35 26    
  g.2271C > T C 0.836 13 21 1 1.900 0.168
   T 0.164 21 13    
  - ACC 0.193 15 8 3 2.350 0.503
  - GTT 0.146 10 16    
  - GTC 0.357 15 18    
  - GCC 0.304 21 19    
DRD 1 (HM754213) g.1013C > G > T C 0.500 47 35 2 9.485 0.009*
   G 0.424 28 46    
   T 0.076 7 1    
  g.1655C > T C 0.795 26 17 1 1.898 0.168
   T 0.205 17 26    
  - GT 0.205 5 17 3 10.068 0.018*
  - TC 0.066 7 1    
  - CC 0.511 30 18    
  - GC 0.218 6 12    
GABRA 6 (HM754216) g. 176C > T T 0.266 30 37 1 0.546 0.460
   C 0.734 37 30    
  g.444A > T A 0.576 29 35 1 0.563 0.453
   T 0.424 35 29    
  g.1520G > A T 0.590 29 34 1 0.397 0.529
   G 0.410 34 29    
  - TTG 0.521 15 18 2 4.510 0.123
  - CAT 0.257 15 17    
  - CTG 0.132 11 3    
5-HTR2C (HM754211) g.675C > T A 0.606 15 7 1 2.909 0.088
   G 0.394 7 15    
  1. Note: T: Transmission; UT: Untransmission; LRS: likelihood ratio statistic. The likelihood ratio statistic is minus twice the difference in log-likelihoods; P: P value from the overall test of association; DF: degree of freedom;
  2. *: significant in statistics
  3. 1. Rare haplotypes were excluded from association study.