Table 3 Comparison of prediction accuracies for HLA predictive models built with and without imputed SNPs
From: Empirical evaluations of analytical issues arising from predicting HLA alleles using multiple SNPs
| Â | Â | Without Imputed SNPs | With Imputed SNPs | ||||
|---|---|---|---|---|---|---|---|
| Â | HLA- | CT = 0 | CT = 0.5 | CT = 0.9 | CT = 0 | CT = 0.5 | CT = 0.9 |
Intermediate Resolution | A | 97 | 97(100)* | 99(87) | 98 | 98(100) | 99(89) |
| Â | B | 95 | 95(99) | 98(86) | 96 | 96(100) | 98(88) |
| Â | C | 98 | 98(100) | 98(97) | 99 | 99(99) | 99(97) |
| Â | DRB1 | 93 | 93(99) | 97(78) | 93 | 93(100) | 98(78) |
| Â | DQB1 | 96 | 97(99) | 98(95) | 97 | 97(100) | 97(94) |
High Resolution | A | 95 | 95(100) | 97(86) | 97 | 97(100) | 98(86) |
| Â | B | 93 | 93(98) | 96(78) | 93 | 94(97) | 96(72) |
| Â | C | 97 | 97(99) | 98(95) | 98 | 98(100) | 98(93) |
| Â | DRB1 | 83 | 87(85) | 94(48) | 87 | 88(95) | 95(59) |
| Â | DQB1 | 94 | 95(100) | 95(94) | 95 | 95(100) | 96(96) |