Graphical comparison of mean predictions. Risk models representing a masking effect of the genetic factor, high risk scenario, n = 1,000 + 1,000. Graphical comparison of mean predictions for all u′= 0, 0.1, 0.2,…,100 and g = 0,1,2, where the rows relate to the different theoretic risk models. Green lines refer to the theoretic risk model, blue lines to the mean predictions, and red lines to the pointwise prediction intervals. DV = design variables.