Table 1 Power of VC-score tests under different sample sizes
From: A variance component based multi-marker association test using family and unrelated data
Design | h2 | Significance level (α) | ||
|---|---|---|---|---|
0.05 | 1 × 10-5 | 1 × 10-6 | ||
I. 500/3000 | ||||
0.01 | 0.840 | 0.355 | 0.270 | |
0.02 | 1 | 0.855 | 0.780 | |
0.03 | 1 | 0.985 | 0.980 | |
II. 750/2000 | ||||
0.01 | 0.890 | 0.345 | 0.235 | |
0.02 | 1 | 0.825 | 0.725 | |
0.03 | 1 | 0.975 | 0.970 | |
III. 750a/2000 | ||||
0.01 | 0.94 | 0.435 | 0.335 | |
0.02 | 1 | 0.92 | 0.880 | |
0.03 | 1 | 1 | 0.990 | |