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Table 4 A summary of the tests for departures from neutrality for an 8063bp region of CYP3A5

From: Molecular diversity and population structure at the Cytochrome P450 3A5 gene in Africa

 

Global populations

Ethiopian populations

 

African-Americans

Europeans

Han Chinese

Afar

Amhara

Anuak

Maale

Oromo

Sample size

23

24

23

75

76

76

76

76

Nucleotide diversity (Ï€)

5.4 x 10-4

9 x 10-5

1.1 x 10-4

2.1 x 10-4

2.5 x 10-4

3.6 x 10-4

3.5 x 10-4

2.2 x 10-4

McDonald-Kreitman test

0.475

0.50

0.777

0.462

0.475

0.576

1.00

0.777

Tajima’s D

−1.04

−1.92

−1.21

−1.46

−1.13

−1.26

−0.96

−1.79

Fu and Li’s D*

−0.97

−2.86

−1.82

−1.19

0.12

−2.72

−0.11

−1.05

Fu and Li’s F*

−1.17

−3.00

−1.91

−1.54

−0.43

−2.57

−0.53

−1.58

Fu and Li’s D

−0.64

−1.37

−1.45

−1.56

−0.08

−1.93

0.73

−0.96

Fu and Li’s F

−0.92

−1.81

−1.55

−1.79

−0.52

−1.96

0.13

−1.48

Fu’s F S

−31.06

−5.71

−1.54

−9.48

−11.74

−18.44

−11.08

−22.84

Strobeck’s S

1.00

0.999

0.929

1.00

1.00

1.00

1.00

1.00

Fay and Wu’s H statistic

−0.13140

−3.25532

−1.89372

0.10774

−0.23998

−0.47177

−0.87086

−1.75514

  1. Statistically significant departures from neutrality, following Bonferonni correction (correction for 8 tests; adjusted p≤0.00625) are shown in bold.