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Table 6 Occurrence of TGCTs-affected males of various Dnd1 genotypes

From: Contrasting effects of Deadend1 (Dnd1) gain and loss of function mutations on allelic inheritance, testicular cancer, and intestinal polyposis

Genotype

Affected

Unaffected

Affected males (%) (%)

ǂDnd1+/+

6

34

15%

ǂDnd1+/KO

1

28

3%

ǂDnd1+/Ter

14

27

34%

ǂDnd1KO/Ter

7

13

35%

*Dnd1+/Ter

35

55

ǂ39%

*Dnd1Ter/Ter

45

1

ǂ98%

  1. Dnd1+/KO and Dnd1+/Ter animals were intercrossed to test for occurrence of males with at least one TGCT. ǂ Offspring from Dnd1+/KO × Dnd1+/Ter crosses; * offspring from Dnd1+/Ter × Dnd1+/Ter. ǂData are from Zechel et al.[51].
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BMC Genomic Data

ISSN: 2730-6844

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