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Table 3 Estimated two-locus haplotype frequencies and linkage disequilibrium coefficients in the seven ethnic groups

From: Study of human SP-A, SP-B and SP-D loci: allele frequencies, linkage disequilibrium and heterozygosity in different races and ethnic groups

Loci Haplotype Black Am Nigerian Mexican German Greek Netherlands White Am
   freq (a) LD (b) freq LD freq LD freq LD freq LD freq LD freq LD
B-18(A/C) AC 0.63 0.08 0.57 0 0.52 0.20 0.55 0.17 0.52 0.22 0.71 0.16 0.52 0.16
-- CA 0.13 0.08 0.06 0 0.40 0.20 0.32 0.17 0.42 0.22 0.23 0.16 0.32 0.16
B1013(A/C) CC 0.24 -0.08 0.24 0 0.07 -0.20 0.08 -0.17 0.03 -0.22 0.04 -0.16 0.10 -0.16
  AA 0 -0.08 0.13 0 0.02 -0.20 0.05 -0.17 0.03 -0.22 0.02 -0.16 0.06 -0.16
DA11(C/T) CG 0.40 0.04 0.38 0 0.39 0.18 0.38 0.12 0.34 0.05 0.27 0.14 0.40 0.16
-- TA 0.10 0.04 0 0 0.48 0.18 0.36 0.12 0.26 0.05 0.54 0.14 0.39 0.16
DA160(A/G) TG 0.49 -0.04 0.62 0 0.12 -0.18 0.20 -0.12 0.27 -0.05 0.17 -0.14 0.2 -0.16
  CA 0 -0.04 0 0 0.01 -0.18 0.07 -0.12 0.13 -0.05 0.03 -0.14 4E-3 -0.16
SP-A2 1A06A2 0.19 0.07 0.20 0.08 0.47 0.22 0.55 0.23 0.50 0.23 0.60 0.18 0.50 0.20
-- 1A16A3 0.11 0.02 0.11 -0.07 0.09 0.07 0.15 0.11 0.17 0.11 0.07 0.06 0.13 0.10
SP-A1(c) 1A26A3 0.14 0.07 0.18 0.09 0.05 0.04 0.05 0.03 0.06 0.03 0.03 0.02 0.04 0.02
  1A06A3 0.10 -0.01 0.08 -0.03 0.04 -0.06 0.03 -0.14 0.03 -0.13 0.04 -0.08 0.03 -0.10
  1. (a) Estimated haplotype frequency (b) Estimated linkage disequilibrium coefficient (c) only common haplotypes are shown here.