A simple nonparametric multipoint procedure to test for linkage through mothers or fathers as well as imprinting effects in the presence of linkage

Table 1 True type I error of the tests associated with the nominal values of 1% and 5% for the expected values of the test statistics.

Simulations under sex-equal maps
Nominal type I error and interval bounds	Unlinked			Linked

1%	0.0099	0.0144	0.0084	0.0105
5%	0.0511	0.0500	0.0478	0.0495
Lower Cl	-0.0099 ^a	-0.0141	-0.0221	-0.0354
Upper Cl	-0.0289	0.0251	0.0164	0.0038

^aBold indicates 95% confidence interval boundary.
Simulations were performed in a region unlinked to any susceptibility gene and a region linked to a susceptibility gene.

ISSN: 2730-6844