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Table 4 Summary of linkage results for ALDX1

From: A genome-wide linkage analysis of alcoholism on microsatellite and single-nucleotide polymorphism data, using alcohol dependence phenotypes and electroencephalogram measures

   Affymetrix SNPs Illumina SNPs Microsatellites Comb3
Chr Location (cM) LOD (p) IC/Chr LOD (p) IC/Chr LOD (p) IC/Chr LOD (p) IC/Chr
1 (138–148) 1.060 (0.014) 0.942 (0.02) 1.330 (0.007) 0.932 (0.02)   0.832 (0.07) 0.950 (0.020) 0.972 (0.01)
2 (10–30) 1.140 (0.011) 0.948(0.02) 1.740 (0.002) 0.934 (0.02) 1.51 (0.004) 0.845 (0.08) 1.440 (0.005) 0.975 (0.01)
  (114–125) 1.100 (0.012)   0.700 (0.040)     1.080 (0.013)  
  (134–147) 1.100 (0.012)   1.540 (0.004)     1.180 (0.010)  
  (228–252) 1.720 (0.002)       1.660 (0.003)  
6 (20–24) 0.810 (0.030) 0.947 (0.02) 0.660 (0.040) 0.935 (0.02)   0.803 (0.09) 0.940 (0.020) 0.974 (0.01)
  (183–190)    2.150 (0.0008)     1.910 (0.002)  
7 (3–19) 1.350 (0.006) 0.944 (0.03) 2.3200 (0.0005) 0.933 (0.02) 0.69 (0.04) 0.898 (0.05) 1.720 (0.002) 0.976 (0.01)
  (29–37) 1.170 (0.010)   0.760 (0.030)     1.060 (0.014)  
  (54–62) 0.980 (0.020)   0.740 (0.030)   1.22 (0.009)   1.230 (0.009)  
  (83–119) 2.2500 (0.0006)   1.97 (0.0013)   1.72 (0.002)   2.5200 (0.0003)  
9 (141–142) 0.660 (0.040) 0.947 (0.02) 0.690 (0.040) 0.926 (0.02)   0.782 (0.10) 0.770 (0.030) 0.974 (0.01)
10 (122–128) 0.750 (0.030) 0.943 (0.02) 0.650 (0.040) 0.924 (0.03)   0.664 (0.08)   0.967 (0.01)
  (149–179) 1.9900 (0.0012)   1.750 (0.002)   0.94 (0.02)   1.770 (0.002)  
11 (117–130) 1.280 (0.008) 0.946 (0.02) 1.030 (0.015) 0.924 (0.02) 1.39 (0.006) 0.709 (0.07) 1.450 (0.005) 0.968(0.01)
12 (0–5) 1.150 (0.011) 0.944 (0.02)   0.929 (0.03)   0.816 (0.08)   0.974 (0.01)
  (121–125) 0.830 (0.030)   0.78 (0.03)     0.800 (0.030)  
  (167–172) 0.700 (0.040)   0.930 (0.020)      
13 (81–102) 1.550 (0.004) 0.945 (0.02) 1.220 (0.009) 0.931 (0.02)   0.802 (0.10) 1.460 (0.005) 0.972 (0.01)
17 (34–36)   0.922 (0.05)   0.914 (0.03) 1.110 (0.012) 0.694 (0.08) 0.750 (0.030) 0.961 (0.02)
  (121–123)    0.800 (0.030)      
18 (93–107) 0.960 (0.020) 0.940 (0.02) 0.720 (0.030) 0.918 (0.04)   0.548 (0.06) 0.910 (0.020) 0.959 (0.02)
X (30–46) 2.0500 (0.0011) 0.915 (0.03) 1.520 (0.004) 0.902 (0.08)   0.744 (0.17) 1.460 (0.005) 0.947 (0.03)
  1. Summary of maximum LOD scores and the corresponding p-values (<0.05) for linkage regions for alcohol dependence phenotype ALDX1. Results are shown for microsatellites, Affymetrix SNPs, Illumina SNPs and the combined data (Comb3). The mean and standard deviation of IC are given for each chromosome. Bold text indicate the most significant region on chromosome 7.