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Table 1 Single-point LOD scores at five microsatellite markers at the end of chromosome 3.

From: Modeling the effect of an associated single-nucleotide polymorphism in linkage studies

Model and SNPs Chromosomes
  D3S0123 D3S0124 D3S0125 D3S0126 D3S0127
Null model (linkage only)           
  l1a l1 l1 l1 l1
  1.65 4.51 0.41 1.97 3.06
Including parental SNP genotypes           
  l2 – l1c l2b l2 – l1 l2 l2 – l1 l2 l2 – l1 l2 l2 – l1 l2
   B03T3056 0.33 1.98 0.22 4.73 0.10 0.51 0.42 2.39 0.25 3.31
   B03T3057 0.00 1.65 0.02 4.53 0.04 0.46 0.02 1.99 0.03 3.09
   B03T3066 0.17 1.82 0.03 4.54 0.11 0.54 0.00 1.97 0.42 3.48
Including siblings' SNP genotypes           
  l2 – l1c l2b l2 – l1 l2 l2 – l1 l2 l2 – l1 l2 l2 – l1 l2
   B03T3056 0.60 2.25 0.64 5.15 0.02 0.43 0.18 2.15 1.10 4.16
   B03T3057 0.81 2.46 0.13 4.64 0.17 0.58 0.49 2.46 0.11 3.17
   B03T3066 0.78 2.43 0.39 4.90 0.66 1.07 0.10 2.07 0.15 3.21
  1. al1is LOD score under linkage only (one degree of freedom)
  2. bl2is LOD score for linkage including SNP genotypes (two degrees of freedom)
  3. cl2 – l1is LOD score for comparing model with SNP genotypes to model without SNP genotypes (one degree of freedom)