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Table 3 Classification of the selection methods for the power of the subsets to detect an association

From: Selection of SNP subsets for association studies in candidate genes: comparison of the power of different strategies to detect single disease susceptibility locus effects

  Method I (Johnson et al.) Method II (Stram et al.) Method III (Cousin et al.) Method IV 0.5 (Carlson et al.) Method IV 0.8 (Carlson et al.)
  haplot. testsa SL testsb haplot. testsa SL testsb haplot. testsa SL testsb haplot. testsa SL testsb haplot. testsa SL testsb
C3AR1 5 5 4 4 1 3 1 1 1 1
CCR2 5 5 1 4 1 1 1 3 1 1
CEBPB 5 4 5 4 1 1 2 2 3 3
CSF2 4 5 5 4 1 1 1 3 1 1
FCN3 5 5 1 1 1 1 1 1 1 1
FGL2 1 1 1 1 1 1 1 1 1 1
IFNG 5 5 4 3 2 1 1 4 2 1
IL13 3 5 5 4 4 1 2 3 1 1
IL24 5 5 2 1 1 4 2 1 2 1
IL9 1 2 5 4 1 2 4 5 1 1
LTA 4 5 4 4 1 1 1 3 3 2
LTB 5 5 1 1 1 1 1 1 1 1
MC1R 2 5 4 3 3 4 1 2 4 1
PLAU 4 5 5 4 3 3 1 2 2 1
PROCR 1 1 1 1 1 1 1 1 1 1
RELA 5 5 1 4 1 1 1 1 1 1
SERPINC1 4 5 5 1 1 2 2 4 3 3
TNF 1 1 4 4 3 3 2 2 4 5
TRADD 5 5 3 4 3 1 1 2 1 2
VTN 4 4 2 2 5 5 1 1 2 2
total 74 83 63 58 36 38 28 43 36 31
final rank 5 5 4 4 2 2 1 3 2 1
  1. ahaplotype tests
  2. bSingle Locus tests