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Table 3 Classification of the selection methods for the power of the subsets to detect an association

From: Selection of SNP subsets for association studies in candidate genes: comparison of the power of different strategies to detect single disease susceptibility locus effects

 

Method I (Johnson et al.)

Method II (Stram et al.)

Method III (Cousin et al.)

Method IV 0.5 (Carlson et al.)

Method IV 0.8 (Carlson et al.)

 

haplot. testsa

SL testsb

haplot. testsa

SL testsb

haplot. testsa

SL testsb

haplot. testsa

SL testsb

haplot. testsa

SL testsb

C3AR1

5

5

4

4

1

3

1

1

1

1

CCR2

5

5

1

4

1

1

1

3

1

1

CEBPB

5

4

5

4

1

1

2

2

3

3

CSF2

4

5

5

4

1

1

1

3

1

1

FCN3

5

5

1

1

1

1

1

1

1

1

FGL2

1

1

1

1

1

1

1

1

1

1

IFNG

5

5

4

3

2

1

1

4

2

1

IL13

3

5

5

4

4

1

2

3

1

1

IL24

5

5

2

1

1

4

2

1

2

1

IL9

1

2

5

4

1

2

4

5

1

1

LTA

4

5

4

4

1

1

1

3

3

2

LTB

5

5

1

1

1

1

1

1

1

1

MC1R

2

5

4

3

3

4

1

2

4

1

PLAU

4

5

5

4

3

3

1

2

2

1

PROCR

1

1

1

1

1

1

1

1

1

1

RELA

5

5

1

4

1

1

1

1

1

1

SERPINC1

4

5

5

1

1

2

2

4

3

3

TNF

1

1

4

4

3

3

2

2

4

5

TRADD

5

5

3

4

3

1

1

2

1

2

VTN

4

4

2

2

5

5

1

1

2

2

total

74

83

63

58

36

38

28

43

36

31

final rank

5

5

4

4

2

2

1

3

2

1

  1. ahaplotype tests
  2. bSingle Locus tests