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Table 2 Error rates obtained according to the level of missing information in the APOE and simulated datasets

From: Computation of haplotypes on SNPs subsets: advantage of the "global method"

APOE
MD Method IER SimER IF Res rate
0% Global 1.94% 0.45% 0.986 100%
  Local 4.88% 1.22% 0.97 100%
2% Global 2.24% 0.48% 0.986 100%
  Local 5.12% 1.19% 0.972 100%
5% Global 3.20% 0.54% 0.987 100%
  Local 5.64% 1.83% 0.978 100%
10% Global 4.41% 0.68% 0.979 100%
  Local 6.89% 1.91% 0.972 100%
15% Global 6.98% 1.09% 0.974 100%
  Local 10.33% 1.97% 0.964 99.75%
20% Global 12.35% 2.09% 0.954 100%
  Local 15.21% 2.54% 0.943 99.21%
Simulated
MD Method IER SimER IF Res rate
0% Global 0.14% 0.02% 0.996 100%
  Local 0.81% 0.10% 0.989 100%
2% Global 0.19% 0.02% 0.989 100%
  Local 1.26% 0.13% 0.982 100%
5% Global 0.25% 0.03% 0.982 100%
  Local 1.46% 0.18% 0.975 100%
10% Global 0.46% 0.05% 0.968 100%
  Local 2.65% 0.32% 0.961 100%
15% Global 0.83% 0.09% 0.954 100%
  Local 4.80% 0.59% 0.947 100%
20% Global 1.51% 0.16% 0.941 100%
  Local 8.70% 1.06% 0.934 100%
  1. Summary of the average error rates found when working with subhaplotypes based on 4 SNPs out of 9 in the APOE genomic dataset and 10 SNPs out of 30 in the 10 simulated datasets.
  2. IER: individual error rate, Res Rate: resolution rate, SimER: similarity error rate, MD: Missing data, IF: frequency error rate (see Material and Methods).