Separation of base allele and sampling term effects gives new insights in variance component QTL analysis

BMC Genomic Data

Table 1 Setup for the simulations with a fully informative marker. 800 F₂ individuals were simulated with phenotype equal to the sum of the additive QTL effect, dominance QTL effect and residual effect

Percentage of the phenotypic variance explained by the QTL^a	Additive effect (a)^b	Dominance effect (d)	Residual variance
5% additive QTL	3.162	0	95
10% additive QTL	4.472	0	90
20% additive QTL	6.324	0	80
20% add. QTL and 10% dominance	6.324	3.162	70

^a Expected additive QTL variance $σ_{v}^{2}$ equal to 0.5a²
^b The two alternative homozygous genotypes had additive effect a and -a in the simulated data

ISSN: 2730-6844