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Table 2 Alleles frequencies and allelic relative risks in power simulation.

From: Trend-TDT – a transmission/disequilibrium based association test on functional mini/microsatellites

Designation

Allele length

Notes

 

1

2

3

4

5

6

 

Allele Frequencies

       

   F6.eq

1/6

1/6

1/6

1/6

1/6

1/6

Equal allele frequencies.

   F6.rd

.15

.20

.10

.40

.10

.05

Randomized allele frequencies.

   F6.bi

.10

.10

.30

.30

.10

.10

There exist two major alleles.

Relative Risk

       

   RR(lin)

1

1.4

1.8

2.2

2.6

3

RRs increase linearly along with allele length.

   RR(thr4) §

1

1

1

3

3

3

RRs increase above a threshold of allele length.

  1. § the number in the bracket denotes the first allele with higher risk.
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BMC Genomic Data

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