Table 2 SNPs according to position, function, predicted changes in amino acid and novelty.
Gene | CFA* | Region | Allel | Function† | Codon position | Protein residue‡ | Aa position | Novelty of SNP§ | Reference sequence|| |
|---|---|---|---|---|---|---|---|---|---|
TH | 18 | EX 13 | C/T | syn | 3 | Asp [D] | 482 | Novel | [GenBank: NM_001002966.1] |
SLC6A3 | 34 | EX 9 | A/G | syn | 3 | Gly [G] | 418 | Novel | [GenBank: XM_846543.1] |
EX 10 | C/T | syn | 3 | Asp [D] | 468 | Publ. – rs23877306 | [GenBank: XM_846543.1] | ||
EX 10 | A/G | syn | 3 | Ala [A] | 471 | Novel | [GenBank: XM_846543.1] | ||
EX 11 | C/T | syn | 3 | Asp [D] | 498 | Novel | [GenBank: XM_846543.1] | ||
DRD1 | 4 | EX 1 | A/G | syn | 3 | Ala [A] | 84 | Novel | [GenBank: XM_546227.2] |
EX 1 | C/T | syn | 3 | Gly [G] | 88 | Novel | [GenBank: XM_546227.2] | ||
EX 1 | C/T | syn | 3 | Val [V] | 236 | Novel | [GenBank: XM_546227.2] | ||
EX 1 | C/T | ns | 2 | Thr [T]/Met [M] | 354 | Novel | [GenBank: XM_546227.2] | ||
DRD2 | 5 | EX 2 | C/T | syn | 3 | Asn [N] | 23 | Novel | [GenBank: NM_001003110.1] |
EX 2 | C/T | syn | 3 | Ala [A] | 77 | Novel | [GenBank: NM_001003110.1] | ||
DRD3 | 33 | EX 4 | C/T | syn | 3 | Cys [C] | 231 | Novel | [GenBank: XM_545106.2] |
EX 6 | A/G | ns | 2 | Gln [Q]/Arg [R] | 294 | Novel | [GenBank: XM_545106.2] | ||
EX 6 | C/T | ns | 1 | Leu [L]/Phe [F] | 341 | Novel | [GenBank: XM_545106.2] | ||
EX 7 | C/T | syn | 3 | Cys [C] | 402 | Novel | [GenBank: XM_545106.2] | ||
DBH | 9 | EX 1 | A/G | syn | 3 | Thr [T] | 17 | Novel | [GenBank: NM_001005263.1] |
EX 2 | A/G | syn | 3 | Gln [Q] | 121 | Novel | [GenBank: NM_001005263.1] | ||
EX 3 | C/T | syn | 3 | Tyr [Y] | 163 | Novel | [GenBank: NM_001005263.1] | ||
EX 4 | A/C | ns | 3 | Lys [K]/Asn [N] | 263 | Novel | [GenBank: NM_001005263.1] | ||
EX 4 | C/T | syn | 3 | Gly [G] | 297 | Novel | [GenBank: NM_001005263.1] | ||
EX 12 | A/G | syn | 3 | Gly [G] | 622 | Novel | [GenBank: NM_001005263.1] | ||
HTR1A | 2 | EX1 | A/C | ns | 1 | Lys [K]/Gln [Q] | 270 | Publ. – rs22855024 | [GenBank: XM_544358.1] |
HTR1B | 12 | EX 1 | A/C | ns | 1 | Ile [I]/Leu [L] | 53 | Novel | [GenBank: NM_001006948.1] |
EX 1 | A/G | syn | 3 | Pro [P] | 82 | Novel | [GenBank: NM_001006948.1] | ||
HTR1D | 2 | EX 1 | C/T | ns | 2 | Ala [A]/Val [V] | 97 | Novel | [GenBank: NM_001003280.1] |
EX 1 | C/T | syn | 3 | Tyr [Y] | 221 | Novel | [GenBank: NM_001003280.1] | ||
EX 1 | A/G | ns | 2 | Glu [E]/Gly [G] | 263 | Publ. – rs22791523 | [GenBank: NM_001003280.1] | ||
EX 1 | C/T | syn | 3 | His [H] | 372 | Novel | [GenBank: NM_001003280.1] | ||
HTR1E | 12 | EX 1 | C/T | syn | 1 | Leu [L] | 39 | Novel | [GenBank: XM_539028.1] |
HTR1F | 31 | EX 1 | C/T | syn | 3 | Arg [R] | 162 | Publ. – rs9250875 | [Ensembl: ENSCAFT00000012417] |
HTR2B | 25 | EX 1 | C/T | ns | 2 | Thr [T]/Ile [I] | 88 | Novel | [GenBank: NM_001024633.1] |
EX 3 | C/T | ns | 2 | Ala [A]/Val [V] | 431 | Novel | [GenBank: NM_001024633.1] | ||
HTR2C | X | EX 6 | A/G | syn | 3 | Pro [P] | 280 | Novel | [GenBank: NM_001006648.1] |
HTR3A | 5 | EX 2 | C/T | ns | 2 | Thr [T]/Met [M] | 64 | Novel | [GenBank: XM_546517.2] |