Pairwise linkage disequilibrium (LD) among the 11 SNPs located at 16q22.1 region. Pairwise LD was measured by the r2 statistic. An r2 value of 1 indicates a complete LD between two SNPs, and an r2 value of 0 indicates a perfect equilibrium. Lower r2 value shows a lower degree of LD. Pairwise D′ values along with LOD scores were displayed in different colors. White indicates D′ <1 and LOD <2; blue indicate D′ = 1 and LOD <2; bright red indicate D′ = 1 and LOD <2; shades of pink/red indicate D′ <1 and LOD ≥2.