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Table 1 Involvement of CAV1 epigenetic modification in cancers

From: Epigenetic modifications of caveolae associated proteins in health and disease

Cancer types Promoter hypermethylation Histone modification CAV1 expression Changes in physiology and pathophysiology
Breast [55] [59] Down-regulated Decreased migration after 5-AZA and TSA treatment [59]
[57]
[43]
[56]
[59]
[58]
Prostate [62]   Down-regulated Not described
  [64]    
  [63]    
Bladder [68]   Down-regulated Not described
Ovarian [71] [71] Down-regulated Over-expression of CAV1, reduced colony formation and increased apoptosis in ovarian cancer cell line [71]
Lung [70]   Down-regulated Over-expression of CAV1, reduced colony formation in lung cancer cell line [70]
Colorectal [72]   Down-regulated Not described
[73]
[74]
Liver [75]   Down-regulated Not described
[77]