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Table 1 Characteristics of studies included in the meta-analysis

From: Genetic association meta-analysis: a new classification to assess ethnicity using the association of MCP-1 -2518 polymorphism and tuberculosis susceptibility as a model

Author, year, reference

Country

Male cases (%)

Age, mean (SD)

Diagnosis of cases

Control source and characteristics

Methods

Africa

      

 Ben-Selma et al., [23]

Tunisia

75

44(-)/-

Clinical and radiological pTB, BCG+

Healthy individuals, same community and ethnicity, BCG+

RFLP

 Arji et al., [24]

Morocco

56

30(16)/38(17)

Clinical and radiological pTB, AFB+, HIV-, HBV-, HCV-

Healthy blood donors

RFLP

 Möller et al., [22]

South Africa

-

-

Clinical and radiological pTB, AFB+, HIV-

Healthy individuals, same community, HIV-

SNPlex genotyping system

 Thye et al., [20]

Ghana

-

-

Clinical and radiological pTB, AFB+, HIV-

Healthy individuals, TST-

Light type-based genotype

 Velez et al., [21]

Guinea- Bissau

60

37(14)/36(12)

Clinical Pulmonary pTB, AFB+, HIV-

Healthy individuals, same community

Real-time PCR

 Velez et al., [21]

Gambia

69

33(14)/ 29(13)

Clinical Pulmonary pTB, AFB+, HIV-

Neighbors, spouses

Real-time PCR

Asia

      

 Flores-Villanueva et al., [10]

Korea

67

38(-)/34(-)

Clinical and radiological pTB, AFB+, culture+, HIV-

Healthy blood donors

RFLP

 Chu et al., [27]

Hong Kong

66

48(18)/31(9)

Clinical pTB, AFB+, HIV-

Healthy blood donors

RFLP

 Xu et al., [29]

China

51

45(14)/42(13)

Clinical and radiological pTB, AFB+, in treatment

Healthy children

SSP-PCR

 Yang et al., [28]

China

66

-

Clinical and radiological pTB, AFB+, in treatment

Surgery and Gynecology patients, no prior TB

RFLP

 Naderi et al., [30]

Persia

22

50(21)/51(13)

Patients with confirmed pTB

Healthy individuals

Tetra-ARMS PCR

 Mishra et al., [26]

India

69

37(7)/38(6)

AFB+ or patients under treatment

Healthy individuals, same ethnicity, AFB-

RFLP

 Alagarasu et al., [25]

India

66

34(10)/31(9)

Clinical and radiological pTB, AFB+, HIV-

Healthy individuals

RFLP

Latin America

      

 Flores-Villanueva et al., [10]

Mexico

68

37(7)/36(7)

Clinical and radiological pTB, AFB+, culture+

Healthy neighbors, 334 TST+, 176 TST-

RFLP

 Ganachari et al., [3]

Mexico

65

36(6)/37(3)

BCG+, clinical and radiological pTB, AFB+, HIV-

Healthy neighbors, TST+, HIV-

Tetra-ARMS

 Ganachari et al., [3]

Peru

58

30(10)/34(9)

Clinical and radiological pTB, AFB+

Healthy individuals

Tetra-ARMS

  1. pTB = pulmonary TB, AFB = acid fast bacilli, BCG, = Bacillus Calmette-Guérin vaccine, HIV = human immune deficiency virus, HBV = Hepatitis B virus, HCV = Hepatitis C virus, TST = tuberculosis skin test, RFLP = restriction fragment length polymorphism, Tetra-ARMS = amplification refractory mutation system-PCR, PCR = polymerase chain reaction