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Table 1 Characteristics of studies included in the meta-analysis

From: Genetic association meta-analysis: a new classification to assess ethnicity using the association of MCP-1 -2518 polymorphism and tuberculosis susceptibility as a model

Author, year, reference Country Male cases (%) Age, mean (SD) Diagnosis of cases Control source and characteristics Methods
Africa       
 Ben-Selma et al., [23] Tunisia 75 44(-)/- Clinical and radiological pTB, BCG+ Healthy individuals, same community and ethnicity, BCG+ RFLP
 Arji et al., [24] Morocco 56 30(16)/38(17) Clinical and radiological pTB, AFB+, HIV-, HBV-, HCV- Healthy blood donors RFLP
 Möller et al., [22] South Africa - - Clinical and radiological pTB, AFB+, HIV- Healthy individuals, same community, HIV- SNPlex genotyping system
 Thye et al., [20] Ghana - - Clinical and radiological pTB, AFB+, HIV- Healthy individuals, TST- Light type-based genotype
 Velez et al., [21] Guinea- Bissau 60 37(14)/36(12) Clinical Pulmonary pTB, AFB+, HIV- Healthy individuals, same community Real-time PCR
 Velez et al., [21] Gambia 69 33(14)/ 29(13) Clinical Pulmonary pTB, AFB+, HIV- Neighbors, spouses Real-time PCR
Asia       
 Flores-Villanueva et al., [10] Korea 67 38(-)/34(-) Clinical and radiological pTB, AFB+, culture+, HIV- Healthy blood donors RFLP
 Chu et al., [27] Hong Kong 66 48(18)/31(9) Clinical pTB, AFB+, HIV- Healthy blood donors RFLP
 Xu et al., [29] China 51 45(14)/42(13) Clinical and radiological pTB, AFB+, in treatment Healthy children SSP-PCR
 Yang et al., [28] China 66 - Clinical and radiological pTB, AFB+, in treatment Surgery and Gynecology patients, no prior TB RFLP
 Naderi et al., [30] Persia 22 50(21)/51(13) Patients with confirmed pTB Healthy individuals Tetra-ARMS PCR
 Mishra et al., [26] India 69 37(7)/38(6) AFB+ or patients under treatment Healthy individuals, same ethnicity, AFB- RFLP
 Alagarasu et al., [25] India 66 34(10)/31(9) Clinical and radiological pTB, AFB+, HIV- Healthy individuals RFLP
Latin America       
 Flores-Villanueva et al., [10] Mexico 68 37(7)/36(7) Clinical and radiological pTB, AFB+, culture+ Healthy neighbors, 334 TST+, 176 TST- RFLP
 Ganachari et al., [3] Mexico 65 36(6)/37(3) BCG+, clinical and radiological pTB, AFB+, HIV- Healthy neighbors, TST+, HIV- Tetra-ARMS
 Ganachari et al., [3] Peru 58 30(10)/34(9) Clinical and radiological pTB, AFB+ Healthy individuals Tetra-ARMS
  1. pTB = pulmonary TB, AFB = acid fast bacilli, BCG, = Bacillus Calmette-Guérin vaccine, HIV = human immune deficiency virus, HBV = Hepatitis B virus, HCV = Hepatitis C virus, TST = tuberculosis skin test, RFLP = restriction fragment length polymorphism, Tetra-ARMS = amplification refractory mutation system-PCR, PCR = polymerase chain reaction