Progress in methods for rare variant association

BMC Genomic Data

Table 1 Contributions from the GAW19 Collapsing Rare Variants working group

Goal	Reference	Trait	Data type	Statistic type
New statistic	Green et al. [77]	Quantitative	Family simulated	Combined burden and variance component
	Jadhav et al. [78]	Dichotomous	Unrelated, simulated	Burden and Variance component
	Zhu et al. [67]	Quantitative	Family simulated	Variance component
Meta-analysis	Katsumata and Fardo [81]	Quantitative	Family and unrelated simulated	Variance component
Meta-analysis	Wang et al. [82]	Quantitative	Family and unrelated real data	Variance component, haplotype model
Method comparison	Wang et al. [57]	Dichotomous	Family simulated	Burden, variance component and an optimal combination

ISSN: 2730-6844