BMC Genomic Data

Table 2 The overall TDR, FDR and MCC of three schemes of scenario 2 with 1000 cases and 1000 controls in each scheme

From: A novel Markov Blanket-based repeated-fishing strategy for capturing phenotype-related biomarkers in big omics data

Methods	Scheme 2			Scheme 3			Scheme 4
Methods	TDR_overall	FDR	MCC	TDR_overall	FDR	MCC	TDR_overall	FDR	MCC
Bonferroni	0.90	0.00	0.94	0.75	0.01	0.86	0.57	0.01	0.75
B-H	0.94	0.02	0.95	0.84	0.04	0.89	0.74	0.03	0.84
LASSO	0.51	0.00	0.71	0.78	0.01	0.88	0.82	0.09	0.86
DASSO-MB	0.54	0.00	0.71	0.45	0.07	0.66	0.36	0.11	0.56
MBRFS	0.98	0.12	0.93	0.92	0.14	0.89	0.96	0.13	0.91

Bonferroni and B-H is the multiply correction methods after χ ² tests
TDR true discovery rate
FDR false discovery rate
MCC matthews correlation coefficience

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ISSN: 2730-6844

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