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Table 1 Mutations identified in the Indigenous population and shared with the Sigma and 1000 Genome Projects. * Frequencies sorted by cases: controls; cases are defined as patients with type 2 diabetes

From: Rare intronic variants of TCF7L2 arising by selective sweeps in an indigenous population from Mexico

1000 Genomes Project Sigma Project Indigenous people
MAF Genotypes MAF Genotypesa Variant
Exonic/Intronic
Gene Gene coordenate dbSNP138 Chr Start End Ref Obs
0.1984 2007(G/G)/451(G/T)/46(T/T)    Intronic 6 Gene 191193 rs56913138 Chr10 114901201 114901201 G T
0.000399 2503(G/G)/1(G/T)/0(T/T)    Intronic 6 Gene 193976 rs188695269 Chr10 114903984 114903984 G A
0.992412 19(T/T)/303(T/C)/2182(C/C)    Intronic 9 Gene 201071 rs176632 Chr10 114911079 114911079 T C
0.002396 2498(C/C)/6(C/G)/0(G/G)    Intronic 9 Gene 209587   Chr10 114919595 114919595 C T
0.129793 2179(C/C)/301(C/A)/24(A/A) 0.0896552 C/C = 1564:1618 C/A = 331:320 A/A = 10:16 Exonic 15 Gene 215361 rs77961654 Chr10 114925369 114925369 C A
   0.000985222 C/C = 1901:1950 C/G = 4:4 Exonic 15 Gene 215363 rs61724286 Chr10 114925371 114925371 C G
  1. aGenotypes
  2. Frequencies sorted cases: controls, the cases defined by patients with type 2 diabetes