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Fig. 3 | BMC Genetics

Fig. 3

From: Identification and integrated analysis of differentially expressed lncRNAs and circRNAs reveal the potential ceRNA networks during PDLSC osteogenic differentiation

Fig. 3

Differentially expressed lncRNAs/circRNAs validated by qRT-PCR. a Convergent primers were designed to detect eight lncRNAs with P < 0.05, FC ≥ 2 and FPKM in at least one of the samples ≥4. LncRNAs coded as TCONS_00019601, TCONS_00227764, TCONS_00254538, TCONS_00198784 and TCONS_00136898 were up-regulated in the induced group compared with the non-induced group, and TCONS_00085268, TCONS_00125934, and TCONS_00115113 were down-regulated. b Divergent primers were designed to detect the circular form of circRNAs with P < 0.05, FC ≥ 2 and RPM in at least one of the samples ≥4. CircRNAs named CDR1-AS, NCOA3, and SKIL were up-regulated in the induced group compared to the non-induced group, and the circRNAs IFF01, NTNG1, PLOD2, SMO, and SMURF2 were down-regulated. The results agreed with the normalized expression of validated lncRNAs and circRNAs shown in Tables 2 and 3. All PCRs were performed in triplicate. The data are represented as means ± SD. *, P < 0.05; **, P < 0.01

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BMC Genomic Data

ISSN: 2730-6844

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