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Table 3 Relative mRNA levels of EMT-related genes in CRC

From: Upregulation of NETO2 gene in colorectal cancer

Gene Frequency of mRNA level changes, % Median of mRNA level changes, n-fold
↑ increased expression ↓ decreased expression
TWIST1 68 (30/44) 5 (2/44) 2.8↑
SNAIL1 80 (35/44) 2 (1/44) 3.3↑
SNAIL2 11 (5/44) 20 (9/44) 1.2↓
ZEB1 9 (4/44) 36 (16/44) 1.5↓
ZEB2 7 (3/44) 45 (20/44) 1.7↓
LEF1 75 (33/44) 2 (1/44) 3.9↑
FOXA1 7 (3/44) 52 (23/44) 2.1↓
FOXA2 59 (26/44) 5 (2/44) 2.5↑
CDH1 5 (2/44) 16 (7/44) 1.3↓
STAT1 25 (11/44) 5 (2/44) 1.4↑
BMP2 2 (1/44) 75 (33/44) 3.2↓
BMP5 7 (3/44) 84 (37/44) 7.6↓
VIM 18 (8/44) 7 (3/44) 1.3↑
SMAD2 0 (0/44) 11 (5/44) 1.4↓
SMAD3 0 (0/44) 11 (5/44) 1.2↓
SMAD4 0 (0/44) 23 (10/44) 1.5↓
SMAD7 0 (0/44) 43 (19/44) 1.8↓
  1. Note: Significant frequencies (p < 0.05) are marked in bold