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Table 1 List of studied disorders and sample size of the respective GWAS studies

From: Can polygenic risk scores help explain disease prevalence differences around the world? A worldwide investigation

Category

Disorder

GWAS Pop. (Eur/Trans)

World Prevalence

SNP Heritability

 Study References

Cardiovascular

Coronary Artery Disease (CAD)

Eur

2.65

0.099

[14]

Neurological

Alzheimer’s Disease (AD)

Eur

0.69

0.0145

[13]

Parkinson’s Disease (PD)

Eur

0.11

0.0113

[15]

Metabolic

Type 2 Diabetes (T2D)

Trans

5.89

0.0286

[16]

Obesity (OBY)

Eur

12.23

0.1547

[17]

Chronic Kidney Disease (CKD)

Trans

9.37

0.0246

[18]

Autoimmune

Asthma (AST)

Trans

3.53

0.075

[19]

Type 1 Diabetes (T1D)

Eur

0.30

NA

[23]

Rheumatoid Arthritis (RA)

Trans

0.25

0.143

[22]

Crohn’s Disease (CRD)

Eur

0.07

0.86

[20]

Multiple Sclerosis (MS)

Eur

0.02

0.0492

[21]

Psychiatric

Bipolar Disorder (BPD)

Eur

0.53

0.3

[24]

Schizophrenia (SCZ)

Trans

0.32

0.157

[25]

Major Depressive Disorder (MDD)

Trans

2.49

0.0214

[26]