Fig. 5
From: Exploring the key genomic variation in monkeypox virus during the 2022 outbreak
Protein conformation differences in the key ORFs of RS9. RS1 (green), RS5 (purple), RS8 (red), and RS9 (yellow) were compared. A, Compared with the conformation of J2L, the local structure of S54F RS9 mutant differed substantially. B, Compared with the conformation of C9L, the downstream structure of the R48C mutant differed significantly. C, The predicted protein conformation of C15L showed that RS9 was locally separated near P78S. D, Compared with the protein conformation of A47R, the difference of RS9 near H221Y was significant. E, The AA sequence of A45L was the identical for all RSs and served as a control