Exploring the key genomic variation in monkeypox virus during the 2022 outbreak

BMC Genomic Data

Table 3 Relevant parameters of protein conformation models for the key variable regions

ORF	pLDDT (RS9)	RMSD (RS9 vs. RS8)	Relevant References
J2L	86.1	1.093	[4]
C9L	90.6	2.375	[24]
C15L	78.7	1.572	[25]
A47R	70.2	3.475	[26]^a
J1L	78.1	0.036	[27]
D9L	84.9	0.532	[28]
C3L	80.8	0.313	[29]
C18L	88.3	0.819	[30]^a
C19L	92	0.088	[31]^a
F8L	90.1	0.863	[32]
F9R	95	0.142	[33]^a
G9R	89.4	0.601	[32]
G10R	84.5	0.1	[34]^a
M4R	80.2	0.075	[35]
A19R	87.9	0.212	[36]^a
A24R	89.3	0.122	[26]^a
B21R	62.9	4.615	[37]
J2R	86.1	0.602	[38]^a
J3R	78.1	0.035	None

^aORF has not been studied in monkeypox virus, and the literature is related to isoforms of other orthopoxviruses
Abbreviations: ORF Open reading frame, RS Reference sequence, pLDDT predicted local distance difference test, RMSD Root mean square deviation

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