Table 4 Changes of TFBSs caused by the SNPs in the 5′flanking region of KLF6.
SNP | Allele | Transcription factor | Transcript relative score (≥ 0.85) | Predicted binding site sequence |
|---|---|---|---|---|
g.44,595,327 A > G | A | SOX18 | 0.89 | cagAatag |
| Â | G | GATA2 | 0.99 | gGata |
| Â | Â | GATA1 | 0.95 | gGatag |
| Â | Â | GATA3 | 0.91 | gGatag |
g.44595580G > A | G | EVX2 | 0.91 | tctcattaaG |
| Â | Â | EMX2 | 0.91 | tctcattaaG |
| Â | Â | EVX1 | 0.90 | tctcattaaG |
| Â | A | NR1I3 | 0.91 | ttaaActct |
g.44595695G > A | G | FOXC1 | 0.86 | atggtGta |
| Â | A | FOXL1 | 0.85 | atggtAta |
g.44,595,808 C > T | C | NPAS4 | 0.87 | cttCgtgaggg |
| Â | T | SOX15 | 0.86 | tcttTgtgag |
g.44,596,221 A > C | A | KLF4 | 0.86 | gAaggcaagg |
| Â | C | ATF1 | 0.91 | gttacgCa |
g.44,596,271 C > T | C | HIC2 | 0.91 | gtgcCctgt |
| Â | T | SOX10 | 0.86 | cTctgt |
g.44,596,874 A > G | A | ERG | 0.89 | gggcAggaagggca |
| Â | G | KLF12 | 0.89 | ggggcGgga |