Fig. 2From: Differential lung gene expression changes in C57BL/6 and DBA/2 mice carrying an identical functional Mx1 gene reveals crucial differences in the host responsePCA, Mx1 gene expression and DEGs overview. AÂ PC1 and PC2 of a principle component analysis of the normalized transcriptome expression values from infected and mock-treated mouse lungs. Each dot represents values from a single mouse. BÂ Boxplot for Mx1 gene expression values in each group of mice. Each dot represents the value of a single mouse. Boxes represent the mean and range (25% and 75% quartiles) of normalized log2 transformed expression values per group. CÂ Numbers of up- and down-regulated DEGs for contrasts between the indicated groups of infected B6-Mx1r/r and D2-Mx1r/r, and mock-treated mice at days 3 and 5 p.i. DÂ Venn diagram illustrating overlap of DEGs from contrasts of infected B6-Mx1r/r and D2-Mx1r/r versus mock controls at day 3 p.i. EÂ Venn diagram illustrating overlap of DEGs from contrasts of infected B6-Mx1r/r and D2-Mx1r/r versus mock controls at day 5 p.iBack to article page